Cobamamide and Joint swelling - a phase IV clinical study of FDA data

Summary:

Joint swelling is reported as a side effect among people who take Cobamamide (dibencozide), especially for people who are female, 60+ old, also take Lyrica, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Joint swelling when taking Cobamamide. It is created by eHealthMe based on reports of 1,046 people who have side effects when taking Cobamamide from the FDA, and is updated regularly.

What is Cobamamide?

Cobamamide has active ingredients of dibencozide. eHealthMe is studying from 1,046 Cobamamide users. Check the latest studies of Cobamamide.

What is Joint swelling?

Joint swelling is found to be associated with 2,120 drugs and 2,934 conditions by eHealthMe. Check the latest studies of Joint swelling.

On Jul, 19, 2026

1,046 people reported to have side effects when taking Cobamamide.
Among them, 52 people (4.97%) have Joint swelling.

Among these 52 people:

What is the gender of people who have Joint swelling when taking Cobamamide? *

female: 90.91 %
male: 9.09 %

What is the age of people who have Joint swelling when taking Cobamamide? *

What are other drugs people take besides Cobamamide? *

What are other side effects people have besides Joint swelling? *

Joint Pain: 39 people, 75.00%
Back Pain: 34 people, 65.38%
Fatigue (feeling of tiredness): 33 people, 63.46%
Drug Ineffective: 26 people, 50.00%
Sleep Disorder: 20 people, 38.46%
Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 19 people, 36.54%
Dementia (madness): 19 people, 36.54%
Thyroid Diseases: 19 people, 36.54%
Fall: 19 people, 36.54%
Synovitis (inflammation of the synovial membrane): 19 people, 36.54%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 20 people, 38.46%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 11 people, 21.15%
Swallowing Difficulty: 11 people, 21.15%
Indigestion: 11 people, 21.15%
Fungal Infection: 8 people, 15.38%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 9.62%
Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 5 people, 9.62%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 3.85%
Pain: 2 people, 3.85%
Nausea And Vomiting: 2 people, 3.85%

* Approximation only. Some reports may have incomplete information.

Do you take Cobamamide and have Joint swelling?

- Check whether Joint swelling is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cobamamide:

Cobamamide (1,046 reports)

Joint swelling treatments and more:

Joint swelling (143,797 reports)

Browse all side effects of Cobamamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Joint swelling:

Joint swelling (2,120 drugs)

Browse all the conditions that are associated with Joint swelling:

Joint swelling (2,934 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on dibencozide (the active ingredients of Cobamamide) and Cobamamide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.