Harvoni and Valcyte drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Harvoni (ledipasvir; sofosbuvir) and Valcyte (valganciclovir hydrochloride). Common drug interactions include anaemia among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Harvoni and Valcyte. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Harvoni?

Harvoni has active ingredients of ledipasvir; sofosbuvir. eHealthMe is studying from 19,858 Harvoni users. Check the latest studies of Harvoni.

What is Valcyte?

Valcyte has active ingredients of valganciclovir hydrochloride. It is often used in cmv - immunocompromised host. eHealthMe is studying from 6,409 Valcyte users. Check the latest studies of Valcyte.

On Jul, 26, 2026

16 people who take Harvoni and Valcyte together, and have interactions are studied.

What are the common drug interactions of Harvoni and Valcyte, by gender? *:

female:

Anaemia (lack of blood)
Bile duct stenosis (abnormal narrowing of the common bile duct)
Blood bilirubin increased
Decreased appetite
Kidney transplant rejection
Liver transplant
Vomiting

male:

Arthralgia (joint pain)
Femoral neck fracture (neck of femur bone fracture)
Hallucination (an experience involving the perception of something not present)
Hepatitis c virus test positive
Immunosuppression
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Mitral valve prolapse (heart's mitral valve doesn't work well)
Night sweats (sweating in night)
Oedema peripheral (superficial swelling)
Osmotic demyelination syndrome (increased serum sodium level leads to hyponatremic encephalopathy)

What are the common drug interactions of Harvoni and Valcyte, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Bile duct stenosis (abnormal narrowing of the common bile duct)
Blood bilirubin increased
Cholangitis (infection of the bile duct)
Diarrhoea
Osmotic demyelination syndrome (increased serum sodium level leads to hyponatremic encephalopathy)
Sepsis (a severe blood infection that can lead to organ failure and death)

60+:

Anaemia (lack of blood)
Arthralgia (joint pain)
Liver transplant
Night sweats (sweating in night)
Oedema peripheral (superficial swelling)
Pneumonia
Respiratory failure (inadequate gas exchange by the respiratory system)
Staphylococcal sepsis (blood infection by an infection with staphylococcus bacteria)
Vomiting
Femoral neck fracture (neck of femur bone fracture)

What are the existing conditions these people have? *

Hepatitis C: 12 people, 75.00%
Immunodeficiency Disorders: 1 person, 6.25%
Hypotension (abnormally low blood pressure): 1 person, 6.25%
Heart Disease: 1 person, 6.25%
Disseminated Cytomegaloviral Infection (group of herpes viruses infection): 1 person, 6.25%
Culture Positive: 1 person, 6.25%
Chronic Hepatitis (long lasting inflammation of liver): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

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