Hc and Cordarone drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Hc (hydrocortisone) and Cordarone (amiodarone hydrochloride). Common drug interactions include pneumonia among males.
The phase IV clinical study analyzes what interactions people have when they take Hc and Cordarone. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.
What is Hc?
Hc has active ingredients of hydrocortisone. It is often used in addison's disease. eHealthMe is studying from 1,369 Hc users. Check the latest studies of Hc.
What is Cordarone?
Cordarone has active ingredients of amiodarone hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 22,776 Cordarone users. Check the latest studies of Cordarone.
16 people who take Hc and Cordarone together, and have interactions are studied.

What are the common drug interactions of Hc and Cordarone, by gender? *:
female:
n/a
male:
- Pneumonia
- Actinomycosis (infection that causes sores, or abscesses)
- Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
- Fall
- Gastroenteritis (inflammation of stomach and intestine)
- Herpes zoster
- Hypertension (high blood pressure)
- Hypocalcaemia (levels of calcium in blood serum are abnormally low)
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
- Hypoxia (low oxygen in tissues)
What are the common drug interactions of Hc and Cordarone, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Anaemia of malignant disease
- Ankle fracture
- Anxiety
- Aortic arteriosclerosis (hardening of the aortic arteries)
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Asthenia (weakness)
- Atelectasis (partial or complete collapse of the lung)
- Atrioventricular block first degree (heart block first degree)
- Bacteraemia (presence of bacteria in the blood)
- Basosquamous carcinoma (metatypical basal cell cancer)
60+:
- Actinomycosis (infection that causes sores, or abscesses)
- Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
- Basosquamous carcinoma (metatypical basal cell cancer)
- Benign prostatic hyperplasia (benign enlargement of the prostate)
- Blepharitis (chronic inflammation of the eyelid)
- Brain injury
- Cardiac failure congestive
- Cardiomegaly (increased size of heart than normal)
- Cataract (clouding of the lens inside the eye)
- Cellulitis (infection under the skin)
What are the existing conditions these people have? *
- Osteoporosis (bones weak and more likely to break): 16 people, 100.00%
- Bone Loss: 16 people, 100.00%
- Sleep Disorder: 1 person, 6.25%
- Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 1 person, 6.25%
- Post-Traumatic Stress Disorder: 1 person, 6.25%
- Panic Disorder: 1 person, 6.25%
- Grand Mal Convulsion (a type of generalized seizure that affects the entire brain): 1 person, 6.25%
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1 person, 6.25%
- Aplastic Anemia: 1 person, 6.25%
* Approximation only. Some reports may have incomplete information.
Do you take Hc and Cordarone?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Hc and Cordarone:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Hc:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Cordarone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Hc and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cordarone and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Tesic D, Kostic M, Paunovic D, Jankovic SM, "Analysis of the cost–effectiveness of dronedarone versus amiodarone, propafenone, and sotalol in patients with atrial fibrillation: results for Serbia", Kardiologia Polska (Polish Heart Journal), 2016 Jan .
- Kim DJ, Lee SC, Park GS, Kim GJ, Hwang WT, Lee CS, Lee MH, Hahn DH, Koh HC, "Amiodarone Induced Multiorgan Toxicity in a Patient of Hypertrophic Cardiomyopathy With Atrial Fibrillation", Journal of the Korean Geriatrics Society, 2013 Dec .
- Tesic D, Kostic M, Paunovic D, Jankovic SM, "Analysis of the cost–effectiveness of dronedarone versus amiodarone, propafenone, and sotalol in patients with atrial fibrillation: results for Serbia", Kardiologia Polska (Polish Heart Journal), 2016 Jan .
- Kim DJ, Lee SC, Park GS, Kim GJ, Hwang WT, Lee CS, Lee MH, Hahn DH, Koh HC, "Amiodarone Induced Multiorgan Toxicity in a Patient of Hypertrophic Cardiomyopathy With Atrial Fibrillation", Journal of the Korean Geriatrics Society, 2013 Dec .
How the study uses the data?
The study uses data from the FDA. It is based on hydrocortisone and amiodarone hydrochloride (the active ingredients of Hc and Cordarone, respectively), and Hc and Cordarone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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