Hc and Fenofibrate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hc (hydrocortisone) and Fenofibrate (fenofibrate). Common drug interactions include fatigue among females and muscle spasms among males.

The phase IV clinical study analyzes what interactions people have when they take Hc and Fenofibrate. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Hc?

Hc has active ingredients of hydrocortisone. It is often used in addison's disease. eHealthMe is studying from 1,369 Hc users. Check the latest studies of Hc.

What is Fenofibrate?

Fenofibrate has active ingredients of fenofibrate. It is often used in high blood cholesterol. eHealthMe is studying from 40,457 Fenofibrate users. Check the latest studies of Fenofibrate.

On Aug, 05, 2026

26 people who take Hc and Fenofibrate together, and have interactions are studied.

What are the common drug interactions of Hc and Fenofibrate, by gender? *:

female:

Fatigue (feeling of tiredness)
Dysphonia (speech disorder attributable to a disorder of phonation)
Nausea (feeling of having an urge to vomit)
Pain in extremity
Photopsia (presence of perceived flashes of light)
Swelling
Thrombotic microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury)
Tooth abscess (pus formation in tooth)
Arthralgia (joint pain)
Carotid bruit (sound heard over the carotid artery area during auscultation)

male:

Muscle spasms (muscle contraction)
Blood potassium increased
Myopathy (a muscular disease in which the muscle fibres do not function)
Nausea (feeling of having an urge to vomit)
Rash generalised (rash on most of body parts)
Vomiting
Abdominal distension
Abdominal pain upper
Asthenia (weakness)
Back pain

What are the common drug interactions of Hc and Fenofibrate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Thrombotic microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury)

40-49:

Blood potassium increased
Dysstasia (difficulty in standing)
Hospitalisation
Tremor (trembling or shaking movements in one or more parts of your body)
Malaise (a feeling of general discomfort or uneasiness)
Muscle spasms (muscle contraction)
Nausea (feeling of having an urge to vomit)
Vomiting
Death

50-59:

Abdominal distension
Abdominal pain upper
Asthenia (weakness)
Back pain
Constipation
Dry skin
Dyspepsia (indigestion)
Fatigue (feeling of tiredness)
Pancreatitis (inflammation of pancreas)
Bradycardia (abnormally slow heart action)

60+:

Arthralgia (joint pain)
Muscular weakness (muscle weakness)
Carotid bruit (sound heard over the carotid artery area during auscultation)
Colon adenoma (non cancerous epithelial colon tumour having a glandular origin and structure)
Death
Dyspnoea (difficult or laboured respiration)
Fall
Fatigue (feeling of tiredness)
Food allergy
Haemorrhoids (a swollen vein or group of veins in the region of the anus)

What are the existing conditions these people have? *

Hyperkalemia (damage to or disease of the kidney): 4 people, 15.38%
Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 11.54%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 11.54%
Chronic Myelomonocytic Leukaemia (cancers of the blood-forming cells of the bone marrow): 3 people, 11.54%
Stress And Anxiety: 2 people, 7.69%
Rectal Cancer (cancer of rectum): 2 people, 7.69%
Musculoskeletal Chest Pain (pain in chest muscle or nerve or bones): 2 people, 7.69%
Lung Neoplasm Malignant (cancer tumour of lung): 2 people, 7.69%
Immunodeficiency Disorders: 2 people, 7.69%
Haemorrhoids (a swollen vein or group of veins in the region of the anus): 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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