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Hectorol and Emla drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hectorol (doxercalciferol) and Emla (lidocaine; prilocaine). Common drug interactions include abdominal pain among females and activated partial thromboplastin time prolonged among males.

The phase IV clinical study analyzes what interactions people have when they take Hectorol and Emla. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Hectorol?

Hectorol has active ingredients of doxercalciferol. eHealthMe is studying from 1,815 Hectorol users. Check the latest studies of Hectorol.

What is Emla?

Emla has active ingredients of lidocaine; prilocaine. eHealthMe is studying from 5,276 Emla users. Check the latest studies of Emla.



On Jul, 24, 2026

12 people who take Hectorol and Emla together, and have interactions are studied.

Hectorol and Emla drug interactions.

What are the common drug interactions of Hectorol and Emla, by gender? *:

female:

  1. Abdominal pain
  2. Headache (pain in head)
  3. Nausea (feeling of having an urge to vomit)
  4. Sepsis (a severe blood infection that can lead to organ failure and death)
  5. Chills (felling of cold)
  6. Pyrexia (fever)
  7. Vomiting
  8. Abdominal distension
  9. Arrhythmia (irregular heartbeat)
  10. Cardiac arrest

male:

  1. Activated partial thromboplastin time prolonged
  2. Arteriovenous fistula thrombosis (formation of a blood clot inside a blood vessel-av fistula)
  3. Vomiting
  4. White blood cell count decreased
  5. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  6. Diarrhoea
  7. Drug specific antibody present
  8. Hypoparathyroidism (inadequate secretion of parathyroid hormone resulting in abnormally low levels of calcium in the blood)
  9. Nausea (feeling of having an urge to vomit)
  10. Platelet count decreased

What are the common drug interactions of Hectorol and Emla, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Activated partial thromboplastin time prolonged
  2. Arteriovenous fistula thrombosis (formation of a blood clot inside a blood vessel-av fistula)
  3. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  4. Diarrhoea
  5. Drug specific antibody present
  6. Hypoparathyroidism (inadequate secretion of parathyroid hormone resulting in abnormally low levels of calcium in the blood)
  7. Nausea (feeling of having an urge to vomit)
  8. Platelet count decreased
  9. Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
  10. Therapeutic response decreased (less preventive response)

40-49:

  1. Headache (pain in head)

50-59:

  1. Chronic kidney disease
  2. Diabetic nephropathy (diabetic kidney disease)
  3. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  4. Nephrogenic anaemia (anaemia due to kidney disease)
  5. Renal failure (kidney dysfunction)

60+:

  1. Abdominal pain
  2. Nausea (feeling of having an urge to vomit)
  3. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  4. Dyspnoea (difficult or laboured respiration)
  5. Hypertension (high blood pressure)
  6. Peritonitis bacterial (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs by bacterial)
  7. Renal failure chronic (long lasting kidney dysfunction)
  8. Decreased appetite
  9. Fluid overload (too much fluid in the blood)
  10. Hypotension (abnormally low blood pressure)

What are the existing conditions these people have? *

  1. Hyperparathyroidism Secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary): 3 people, 25.00%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 16.67%
  3. Oedema (fluid collection in tissue): 1 person, 8.33%
  4. Itching: 1 person, 8.33%
  5. Hyperparathyroidism (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium): 1 person, 8.33%
  6. High Blood Cholesterol: 1 person, 8.33%
  7. Gout (uric acid crystals building up in the body): 1 person, 8.33%
  8. Chronic Renal Failure (kidney failure): 1 person, 8.33%
  9. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Hectorol and Emla?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Hectorol and Emla:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Hectorol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Emla:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hectorol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Emla and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on doxercalciferol and lidocaine; prilocaine (the active ingredients of Hectorol and Emla, respectively), and Hectorol and Emla (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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