Hectorol and Levothyroxine sodium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hectorol (doxercalciferol) and Levothyroxine sodium (levothyroxine sodium). Common drug interactions include dizziness among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Hectorol and Levothyroxine sodium. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Hectorol?

Hectorol has active ingredients of doxercalciferol. eHealthMe is studying from 1,815 Hectorol users. Check the latest studies of Hectorol.

What is Levothyroxine sodium?

Levothyroxine sodium has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 129,814 Levothyroxine sodium users. Check the latest studies of Levothyroxine sodium.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

40 people who take Hectorol and Levothyroxine sodium together, and have interactions are studied.

Hectorol and Levothyroxine sodium drug interactions.

What are the common drug interactions of Hectorol and Levothyroxine Sodium, by gender? *:

female:

Dizziness
Dysphagia (a condition in which swallowing is difficult or painful)
Dyspnoea (difficult or laboured respiration)
Flushing (the warm, red condition of human skin)
Sepsis (a severe blood infection that can lead to organ failure and death)
Unresponsive to stimuli
Anxiety
Pyrexia (fever)
Abdominal pain upper
Acute myocardial infarction (acute heart attack)

male:

Fatigue (feeling of tiredness)
Asthenia (weakness)
Dyspnoea exertional (breathlessness or shortness of breath)
Emotional distress
Ischaemic cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease)
Malaise (a feeling of general discomfort or uneasiness)
Multiple injuries
Renal impairment (severely reduced kidney function)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Aplasia pure red cell (type of anaemia affecting the precursors to red blood cells but not to white blood cells)

What are the common drug interactions of Hectorol and Levothyroxine Sodium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Fall
Headache (pain in head)
Hypertension (high blood pressure)
Hypotonia (low muscle tone)
Weakness

40-49:

Acute myocardial infarction (acute heart attack)
Anaemia (lack of blood)
Arteriosclerosis (thickening and hardening of arteries)
Asthenia (weakness)
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Chest discomfort
Chest pain
Dehydration (dryness resulting from the removal of water)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Disorientation (disability in which the senses of time, direction, and recognition of people and places)

50-59:

Peritonitis bacterial (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs by bacterial)

60+:

Hypotension (abnormally low blood pressure)
Diarrhoea
Vomiting
Flushing (the warm, red condition of human skin)
Unresponsive to stimuli
Dizziness
Rash
Aortic aneurysm (enlargement of an aortic artery caused by a weakening of the artery wall)
Arthritis infective (purulent invasion of a joint by an infectious agent which produces arthritis)
Constipation

What are the existing conditions these people have? *

Chronic Renal Failure (kidney failure): 8 people, 20.00%
Anaemia (lack of blood): 4 people, 10.00%
Sepsis (a severe blood infection that can lead to organ failure and death): 3 people, 7.50%
Iron Deficiency Anaemia: 3 people, 7.50%
Hyperparathyroidism Secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary): 3 people, 7.50%
Hyperparathyroidism (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium): 3 people, 7.50%
Gastric Ulcer (stomach ulcer): 3 people, 7.50%
Excoriation (to tear or wear off the skin of): 3 people, 7.50%
Diarrhea: 3 people, 7.50%
Secondary Hypothyroidism (pituitary gland and its failure to secrete tsh): 2 people, 5.00%

* Approximation only. Some reports may have incomplete information.

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