Heparin and Dotarem drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Heparin (heparin sodium) and Dotarem (gadoterate meglumine). Common drug interactions include bacteraemia among females and seizure among males.

The phase IV clinical study analyzes what interactions people have when they take Heparin and Dotarem. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Heparin?

Heparin has active ingredients of heparin sodium. It is often used in blood clots. eHealthMe is studying from 92,141 Heparin users. Check the latest studies of Heparin.

What is Dotarem?

Dotarem has active ingredients of gadoterate meglumine. eHealthMe is studying from 2,749 Dotarem users. Check the latest studies of Dotarem.

On Jul, 20, 2026

21 people who take Heparin and Dotarem together, and have interactions are studied.

What are the common drug interactions of Heparin and Dotarem, by gender? *:

female:

Bacteraemia (presence of bacteria in the blood)
Device failure
Hypoglycaemia (deficiency of glucose in the bloodstream)
Hypotension (abnormally low blood pressure)
Small intestinal obstruction (blockage in small intestine)
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Abdominal pain
Blast cell count increased
Headache (pain in head)
Hypokalaemia (low potassium)

male:

Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Pyrexia (fever)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Haematuria (presence of blood in urine)
Hyperkalaemia (damage to or disease of the kidney)
Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Hypotension (abnormally low blood pressure)
Hypoxia (low oxygen in tissues)
Melaena (the passage of black, tarry stools)

What are the common drug interactions of Heparin and Dotarem, by age (0-1 to 60+)? *:

0-1:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Pneumatosis intestinalis (air or gas in an intestine)

2-9:

n/a

10-19:

Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Acute lymphocytic leukaemia recurrent (cancer in which the bone marrow makes too many lymphocytes-recurrent)
Blood creatinine increased
Blood lactic acid increased
Blood urea increased
Bone marrow failure
Bradycardia (abnormally slow heart action)
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Cytokine storm (over-protective immune response that can actually be fatal)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)

20-29:

Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)

30-39:

n/a

40-49:

Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)

50-59:

Acute respiratory failure
Adenovirus infection

60+:

Bacteraemia (presence of bacteria in the blood)
Device failure
Pyrexia (fever)
Eosinophilia (eosinophil count in the peripheral blood exceeds)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Hypotension (abnormally low blood pressure)
Rash
Small intestinal obstruction (blockage in small intestine)
Abdominal pain
Abscess limb (limb infection)

What are the existing conditions these people have? *

Constipation: 7 people, 33.33%
Fever: 6 people, 28.57%
Nausea And Vomiting: 6 people, 28.57%
Pain: 5 people, 23.81%
Depression: 5 people, 23.81%
Nervous System Disorder (a general class of medical conditions affecting the nervous system): 5 people, 23.81%
Nausea (feeling of having an urge to vomit): 5 people, 23.81%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 19.05%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 4 people, 19.05%
Diabetes: 4 people, 19.05%

* Approximation only. Some reports may have incomplete information.

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