Heparin and Lacosamide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Heparin (heparin sodium) and Lacosamide (lacosamide). Common drug interactions include post procedural infection among females and somnolence among males.

The phase IV clinical study analyzes what interactions people have when they take Heparin and Lacosamide. It is created by eHealthMe based on reports of 89 people who take the same drugs from the FDA, and is updated regularly.

What is Heparin?

Heparin has active ingredients of heparin sodium. It is often used in blood clots. eHealthMe is studying from 92,141 Heparin users. Check the latest studies of Heparin.

What is Lacosamide?

Lacosamide has active ingredients of lacosamide. It is often used in epilepsy. eHealthMe is studying from 16,601 Lacosamide users. Check the latest studies of Lacosamide.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

89 people who take Heparin and Lacosamide together, and have interactions are studied.

Heparin and Lacosamide drug interactions.

What are the common drug interactions of Heparin and Lacosamide, by gender? *:

female:

Post procedural infection
Urinary tract infection
Blood creatinine increased
Blood pressure increased
Blood urea increased
C-reactive protein increased
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Renal artery stenosis (narrowing of renal artery)
Vasculitis (inflammation of a blood vessel or blood vessels)
White blood cell count decreased

male:

Somnolence (a state of near-sleep, a strong desire for sleep)
Premature baby
Metabolic encephalopathy (disorder or disease of the brain due to the body's disability to use energy)
Muscular weakness (muscle weakness)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Delirium (wild excitement)
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Dizziness
Femoral artery aneurysm
Low birth weight baby

What are the common drug interactions of Heparin and Lacosamide, by age (0-1 to 60+)? *:

0-1:

Feeding disorder (when children refuse to eat certain food groups)
Premature baby
Somnolence (a state of near-sleep, a strong desire for sleep)
Drug ineffective
Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Maternal exposure during pregnancy (use of substance during pregnancy)

2-9:

Febrile neutropenia (fever with reduced white blood cells)

10-19:

Blood urea increased
White blood cell count decreased
Blood creatinine increased
Blood pressure increased
C-reactive protein increased
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Pneumonia
Renal artery stenosis (narrowing of renal artery)
Vasculitis (inflammation of a blood vessel or blood vessels)
Anxiety

20-29:

Abortion induced (medically referred abortion)
Maternal exposure during pregnancy (use of substance during pregnancy)

30-39:

Premature delivery
Maternal exposure during pregnancy (use of substance during pregnancy)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Aphasia (damage to the parts of the brain that control language)
Malignant neoplasm progression (cancer tumour came back)
Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
Muscular weakness (muscle weakness)
Mydriasis (a dilation of the pupil)
Pericardial effusion (fluid around the heart)
Procedural complication

40-49:

Chronic tonsillitis (long lasting inflammation of tonsil)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Hypotension (abnormally low blood pressure)
Infection
Pneumonia
Respiratory tract infection
Sepsis (a severe blood infection that can lead to organ failure and death)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Tonsillitis bacterial (bacterial infection of tonsil)
Arterial injury

50-59:

Dyspnoea (difficult or laboured respiration)
Fluid retention (an abnormal accumulation of fluid in the blood)
Pneumonia
Pulmonary arterial pressure increased
Respiratory failure (inadequate gas exchange by the respiratory system)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Muscular weakness (muscle weakness)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Thrombosis (formation of a blood clot inside a blood vessel)
Asthenia (weakness)

60+:

Anaemia (lack of blood)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
International normalised ratio increased
Renal impairment (severely reduced kidney function)
Therapeutic response decreased (less preventive response)
Dehydration (dryness resulting from the removal of water)
Metabolic encephalopathy (disorder or disease of the brain due to the body's disability to use energy)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Delirium (wild excitement)
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)

What are the existing conditions these people have? *

Seizures (abnormal excessive or synchronous neuronal activity in the brain): 24 people, 26.97%
Status Epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 17 people, 19.10%
Pneumonia: 17 people, 19.10%
High Blood Pressure: 16 people, 17.98%
Thrombosis (formation of a blood clot inside a blood vessel): 14 people, 15.73%
Pain: 12 people, 13.48%
Iron Deficiency Anaemia: 10 people, 11.24%
High Risk Pregnancy: 10 people, 11.24%
Haemorrhage Intracranial (bleeding within the skull): 9 people, 10.11%
Cerebral Venous Thrombosis (clot in brains venous blood system): 7 people, 7.87%

* Approximation only. Some reports may have incomplete information.

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