Hepsera and Lasix drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hepsera (adefovir dipivoxil) and Lasix (furosemide). Common drug interactions include blood phosphorus decreased among females and renal impairment among males.

The phase IV clinical study analyzes what interactions people have when they take Hepsera and Lasix. It is created by eHealthMe based on reports of 68 people who take the same drugs from the FDA, and is updated regularly.

What is Hepsera?

Hepsera has active ingredients of adefovir dipivoxil. It is often used in hepatitis b. eHealthMe is studying from 3,113 Hepsera users. Check the latest studies of Hepsera.

What is Lasix?

Lasix has active ingredients of furosemide. It is often used in swelling. eHealthMe is studying from 210,439 Lasix users. Check the latest studies of Lasix.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 21, 2026

68 people who take Hepsera and Lasix together, and have interactions are studied.

What are the common drug interactions of Hepsera and Lasix, by gender? *:

female:

Blood phosphorus decreased
Ascites (accumulation of fluid in the abdominal cavity)
Aphasia (damage to the parts of the brain that control language)
Blood alkaline phosphatase increased
Chest pain
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Back pain
Bradycardia (abnormally slow heart action)
Coma hepatic (accumulation in the bloodstream of toxic substances that are normally removed by the liver leads coma)
Haematocrit decreased

male:

Renal impairment (severely reduced kidney function)
Arthralgia (joint pain)
Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
Osteomalacia (softening of the bones due to a lack of vitamin d)
Decreased appetite
Granulocytopenia (lack of granulocyte)
Pneumonia
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
White blood cell count decreased
Asthenia (weakness)

What are the common drug interactions of Hepsera and Lasix, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Granulocytopenia (lack of granulocyte)
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)

20-29:

n/a

30-39:

Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Erythema multiforme (a type of hypersensitivity reaction)
Platelet count decreased
Pyrexia (fever)
Rash
Red blood cell count decreased
White blood cell count increased

40-49:

Arthralgia (joint pain)
Back pain
Blood alkaline phosphatase increased
Bone marrow failure
Bone pain
Chest pain
Fanconi syndrome acquired (self developed genetic disease of kidney damage due to defective transport system)
Fractured sacrum
Gait disturbance
Glucose urine present

50-59:

Osteoporosis (bones weak and more likely to break)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Platelet count decreased
Protein total decreased
Pyrexia (fever)
Red blood cell count decreased
Renal tubular disorder (disease of kidney tubules)
White blood cell count decreased
Anisocytosis (patient's red blood cells are of unequal size)
Bone marrow failure

60+:

Blood creatinine increased
Diarrhoea
Hepatic neoplasm malignant (liver cancer)
Hyperammonaemia
Metabolic encephalopathy (disorder or disease of the brain due to the body's disability to use energy)
Aphasia (damage to the parts of the brain that control language)
White blood cell count decreased
Arthralgia (joint pain)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Back pain

What are the existing conditions these people have? *

Hepatic Cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue): 21 people, 30.88%
Ascites (accumulation of fluid in the abdominal cavity): 8 people, 11.76%
Hepatic Neoplasm Malignant (liver cancer): 7 people, 10.29%
Gastritis (inflammation of stomach): 6 people, 8.82%
Pain: 5 people, 7.35%
Iron Overload: 5 people, 7.35%
Insomnia (sleeplessness): 5 people, 7.35%
Aplastic Anemia: 5 people, 7.35%
Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 4 people, 5.88%
Oedema (fluid collection in tissue): 4 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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