Hexadrol and Zometa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hexadrol (dexamethasone) and Zometa (zoledronic acid). Common drug interactions include intervertebral disc protrusion among females and osteomyelitis among males.

The phase IV clinical study analyzes what interactions people have when they take Hexadrol and Zometa. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Hexadrol?

Hexadrol has active ingredients of dexamethasone. eHealthMe is studying from 434 Hexadrol users. Check the latest studies of Hexadrol.

What is Zometa?

Zometa has active ingredients of zoledronic acid. It is often used in multiple myeloma. eHealthMe is studying from 71,434 Zometa users. Check the latest studies of Zometa.

On Jul, 16, 2026

26 people who take Hexadrol and Zometa together, and have interactions are studied.

What are the common drug interactions of Hexadrol and Zometa, by gender? *:

female:

Intervertebral disc protrusion (spinal disc protrusion)
Oedema peripheral (superficial swelling)
Spinal osteoarthritis (joint cartilage loss in spine)
Blood glucose increased
Cataract (clouding of the lens inside the eye)
Epistaxis (bleed from the nose)
Lymphadenopathy (disease or enlargement of lymph nodes)
Metastases to lung (cancer spreads to lung)
Mitral valve incompetence (inefficient heart valve)
Neutropenia (an abnormally low number of neutrophils)

male:

Osteomyelitis (infection of bone)
Pain
Bone marrow failure
Bone pain
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
Cataract (clouding of the lens inside the eye)
Chest pain
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Deformity (disfigurement)

What are the common drug interactions of Hexadrol and Zometa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Anaemia (lack of blood)
Anxiety
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cellulitis (infection under the skin)
Facet joint syndrome (problem with movement of the facet joints of the spine)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Intervertebral disc protrusion (spinal disc protrusion)
Oedema peripheral (superficial swelling)
Osteonecrosis of jaw (death of bone of jaw)
Osteoradionecrosis (irradiation of bones causes damage to osteocytes and impairs the blood supply)

50-59:

Mitral valve incompetence (inefficient heart valve)
Myeloma recurrence (recurrence of cancer of the plasma cells - a kind of white blood cell)
Pericardial effusion (fluid around the heart)
Blood pressure increased
Cough
Eosinophil count increased
Haematocrit decreased
Oedema peripheral (superficial swelling)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Red cell distribution width increased

60+:

Malignant neoplasm progression (cancer tumour came back)
Osteomyelitis (infection of bone)
Dizziness
Fatigue (feeling of tiredness)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Platelet count decreased
Somnolence (a state of near-sleep, a strong desire for sleep)
Weight decreased
Actinomycosis (infection that causes sores, or abscesses)

What are the existing conditions these people have? *

Metastases To Bone (cancer spreads to bone): 2 people, 7.69%
Gastric Cancer (stomach cancer): 2 people, 7.69%
Breast Cancer Female: 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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