Hydramine and Baraclude drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hydramine (diphenhydramine hydrochloride) and Baraclude (entecavir). Common drug interactions include abdominal pain among females and decreased appetite among males.

The phase IV clinical study analyzes what interactions people have when they take Hydramine and Baraclude. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Hydramine?

Hydramine has active ingredients of diphenhydramine hydrochloride. It is often used in insomnia. eHealthMe is studying from 114,900 Hydramine users. Check the latest studies of Hydramine.

What is Baraclude?

Baraclude has active ingredients of entecavir. It is often used in hepatitis b. eHealthMe is studying from 6,175 Baraclude users. Check the latest studies of Baraclude.



On Jul, 14, 2026

18 people who take Hydramine and Baraclude together, and have interactions are studied.

Hydramine and Baraclude drug interactions.

What are the common drug interactions of Hydramine and Baraclude, by gender? *:

female:

  1. Abdominal pain
  2. Anaemia (lack of blood)
  3. Anxiety
  4. Cardiac disorder
  5. Cough
  6. Decreased appetite
  7. Depression
  8. Diarrhoea
  9. Dyspnoea (difficult or laboured respiration)
  10. Fatigue (feeling of tiredness)

male:

  1. Decreased appetite
  2. Proteinuria (presence of protein in the urine)
  3. Bk virus infection
  4. Blood alkaline phosphatase increased
  5. Bone marrow failure
  6. Cell-mediated cytotoxicity (a cell destroys target cells)
  7. Chylothorax (collection of lymph fluid around the lung)
  8. Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
  9. Constipation
  10. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)

What are the common drug interactions of Hydramine and Baraclude, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Liver transplant

40-49:

n/a

50-59:

  1. Bk virus infection
  2. Bone marrow failure
  3. Cell-mediated cytotoxicity (a cell destroys target cells)
  4. Chylothorax (collection of lymph fluid around the lung)
  5. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
  6. Dehydration (dryness resulting from the removal of water)
  7. Escherichia infection (bacterial infection by escherichia coli)
  8. Lung disorder (lung disease)
  9. Mucosal inflammation (infection of mucous membrane)
  10. Pleural effusion (water on the lungs)

60+:

  1. Decreased appetite
  2. Anaemia (lack of blood)
  3. Dyspnoea (difficult or laboured respiration)
  4. Fatigue (feeling of tiredness)
  5. Headache (pain in head)
  6. Hypoaesthesia (reduced sense of touch or sensation)
  7. Malaise (a feeling of general discomfort or uneasiness)
  8. Myalgia (muscle pain)
  9. Nausea (feeling of having an urge to vomit)
  10. Oedema peripheral (superficial swelling)

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 5 people, 27.78%
  2. Constipation: 5 people, 27.78%
  3. Cough: 4 people, 22.22%
  4. High Blood Pressure: 4 people, 22.22%
  5. Adult T-Cell Lymphoma/leukaemia (cancer of the immune system's own t-cells): 3 people, 16.67%
  6. Pain: 3 people, 16.67%
  7. Back Pain: 3 people, 16.67%
  8. Diarrhea: 3 people, 16.67%
  9. Hepatocellular Carcinoma (liver cancer): 3 people, 16.67%
  10. Nausea (feeling of having an urge to vomit): 3 people, 16.67%

* Approximation only. Some reports may have incomplete information.

Do you take Hydramine and Baraclude?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Hydramine and Baraclude:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Hydramine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Baraclude:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hydramine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Baraclude and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on diphenhydramine hydrochloride and entecavir (the active ingredients of Hydramine and Baraclude, respectively), and Hydramine and Baraclude (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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