Hydramine and Bendeka drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hydramine (diphenhydramine hydrochloride) and Bendeka (bendamustine hydrochloride). Common drug interactions include infusion site pain among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Hydramine and Bendeka. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Hydramine?

Hydramine has active ingredients of diphenhydramine hydrochloride. It is often used in insomnia. eHealthMe is studying from 114,900 Hydramine users. Check the latest studies of Hydramine.

What is Bendeka?

Bendeka has active ingredients of bendamustine hydrochloride. eHealthMe is studying from 591 Bendeka users. Check the latest studies of Bendeka.

On Jul, 11, 2026

20 people who take Hydramine and Bendeka together, and have interactions are studied.

Hydramine and Bendeka drug interactions.

What are the common drug interactions of Hydramine and Bendeka, by gender? *:

female:

Infusion site pain
Weight fluctuation
Confusional state
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Dizziness
Fall
Influenza
Pneumonia
Renal disorder (kidney disease)

male:

Death
Dehydration (dryness resulting from the removal of water)
Nausea (feeling of having an urge to vomit)
Neoplasm progression (growth of tumour)
Rash
Serum ferritin increased
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Vomiting
Colitis (inflammation of colon)
Diarrhoea

What are the common drug interactions of Hydramine and Bendeka, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Neoplasm progression (growth of tumour)
Death
Dyspnoea (difficult or laboured respiration)
Pneumonia

40-49:

n/a

50-59:

Colitis (inflammation of colon)
Death
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Diffuse large b-cell lymphoma (cancer of b cells, a type of white blood cell)
Gastric haemorrhage (bleeding stomach)
Gastric infection (infection of stomach)
Gastrointestinal bacterial infection (infection of the stomach and intestines caused by bacteria)
Hypotension (abnormally low blood pressure)
Pyrexia (fever)

60+:

Infusion site pain
Weight fluctuation
Nausea (feeling of having an urge to vomit)
Pyrexia (fever)
Rash
Serum ferritin increased
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Vomiting
Disease progression
Hospitalisation

What are the existing conditions these people have? *

Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 6 people, 30.00%
Burkitt Lymphoma (cancer of the lymphatic system): 4 people, 20.00%
Lymph Follicular Hypertrophy (an increase in the size of the lymph node follicles): 3 people, 15.00%
Hodgkin's Lymphoma (cancer originating from white blood cells): 2 people, 10.00%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 2 people, 10.00%
Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 1 person, 5.00%
Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 5.00%
High Blood Pressure: 1 person, 5.00%
Enlarged Prostate: 1 person, 5.00%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

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