Hydramine and Fingolimod drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hydramine (diphenhydramine hydrochloride) and Fingolimod (fingolimod). Common drug interactions include drug ineffective among females and central nervous system lesion among males.

The phase IV clinical study analyzes what interactions people have when they take Hydramine and Fingolimod. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Hydramine?

Hydramine has active ingredients of diphenhydramine hydrochloride. It is often used in insomnia. eHealthMe is studying from 114,900 Hydramine users. Check the latest studies of Hydramine.

What is Fingolimod?

Fingolimod has active ingredients of fingolimod. eHealthMe is studying from 5,150 Fingolimod users. Check the latest studies of Fingolimod.



On Jul, 20, 2026

35 people who take Hydramine and Fingolimod together, and have interactions are studied.

Hydramine and Fingolimod drug interactions.

What are the common drug interactions of Hydramine and Fingolimod, by gender? *:

female:

  1. Drug ineffective
  2. Dyspnoea (difficult or laboured respiration)
  3. Hallucination, auditory (perceiving sounds without auditory stimulus)
  4. Chest pain
  5. Headache (pain in head)
  6. Heart rate decreased
  7. Palpitations (feelings or sensations that your heart is pounding or racing)
  8. Abdominal pain lower
  9. Abnormal behaviour
  10. Back pain

male:

  1. Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
  2. Disease progression
  3. Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain)
  4. Kernig's sign
  5. Lymphopenia (an abnormally low level of lymphocytes in the blood)
  6. Nuchal rigidity (a resistance to flexion of the neck)
  7. Relapsing-remitting multiple sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged)
  8. Anogenital warts
  9. Brain herniation (brain herniation is a potentially deadly side effect of very high intracranial pressure that occurs when a part of the brain is squeezed across structures within the skull)
  10. Brudzinski's sign (indication of meningitis)

What are the common drug interactions of Hydramine and Fingolimod, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Anogenital warts

30-39:

  1. Back pain
  2. Dyspnoea (difficult or laboured respiration)

40-49:

  1. Chest pain
  2. Headache (pain in head)
  3. Heart rate decreased
  4. Palpitations (feelings or sensations that your heart is pounding or racing)
  5. Abdominal pain lower
  6. Brain herniation (brain herniation is a potentially deadly side effect of very high intracranial pressure that occurs when a part of the brain is squeezed across structures within the skull)
  7. Brudzinski's sign (indication of meningitis)
  8. Cerebellar ischaemia (lack of blood supply to cerebeller)
  9. Cough
  10. Cryptococcosis (potentially fatal fungal disease)

50-59:

  1. Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
  2. Disease progression
  3. Relapsing-remitting multiple sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged)
  4. Drug ineffective
  5. Hallucination, auditory (perceiving sounds without auditory stimulus)
  6. Abnormal behaviour
  7. Fatigue (feeling of tiredness)
  8. Headache (pain in head)
  9. Oropharyngeal pain
  10. Pain

60+:

n/a

What are the existing conditions these people have? *

  1. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 18 people, 51.43%
  2. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 16 people, 45.71%
  3. Migraine (headache): 5 people, 14.29%
  4. Restless Leg Syndrome (a powerful urge to move your legs): 4 people, 11.43%
  5. Headache (pain in head): 4 people, 11.43%
  6. Movement - Uncontrolled Or Slow: 3 people, 8.57%
  7. Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 2 people, 5.71%
  8. Encephalitis (inflammation of the brain): 2 people, 5.71%
  9. Cryptococcosis (potentially fatal fungal disease): 2 people, 5.71%
  10. Anogenital Warts: 2 people, 5.71%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Hydramine and Fingolimod:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Hydramine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Fingolimod:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hydramine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Fingolimod and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on diphenhydramine hydrochloride and fingolimod (the active ingredients of Hydramine and Fingolimod, respectively), and Hydramine and Fingolimod (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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