Hydramine and Norethindrone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hydramine (diphenhydramine hydrochloride) and Norethindrone (norethindrone). Common drug interactions include sinusitis among females.

The phase IV clinical study analyzes what interactions people have when they take Hydramine and Norethindrone. It is created by eHealthMe based on reports of 79 people who take the same drugs from the FDA, and is updated regularly.

What is Hydramine?

Hydramine has active ingredients of diphenhydramine hydrochloride. It is often used in insomnia. eHealthMe is studying from 114,900 Hydramine users. Check the latest studies of Hydramine.

What is Norethindrone?

Norethindrone has active ingredients of norethindrone. It is often used in birth control. eHealthMe is studying from 1,610 Norethindrone users. Check the latest studies of Norethindrone.

On Jul, 14, 2026

79 people who take Hydramine and Norethindrone together, and have interactions are studied.

Hydramine and Norethindrone drug interactions.

What are the common drug interactions of Hydramine and Norethindrone, by gender? *:

female:

Sinusitis (inflammation of sinus)
Nasopharyngitis (inflammation of the nasopharynx)
Erythema (redness of the skin)
Fatigue (feeling of tiredness)
Headache (pain in head)
Influenza
Back pain
Drug ineffective
Fall
Respiratory tract infection

male:

n/a

What are the common drug interactions of Hydramine and Norethindrone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
Febrile neutropenia (fever with reduced white blood cells)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Hypertension (high blood pressure)
Mucosal inflammation (infection of mucous membrane)
Epistaxis (bleed from the nose)
Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
Abdominal pain
Anxiety
Back pain

20-29:

Sinusitis (inflammation of sinus)
Sinusitis bacterial (bacterial infection of sinus)
Upper respiratory tract infection
Abdominal pain upper
Back pain
Fatigue (feeling of tiredness)
Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
Headache (pain in head)
Neck pain
Peripheral swelling

30-39:

Blood iron decreased
Drug ineffective
Nausea (feeling of having an urge to vomit)
Pyrexia (fever)
Fall
Monoplegia (a paralysis of a single limb)
Urinary tract infection
Arterial stenosis (abnormal narrowing of the aortic valve in the heart)
Arterial thrombosis (formation of a blood clot inside a blood vessel, obstructing the flow of blood through the circulatory system)
Arthralgia (joint pain)

40-49:

Nasopharyngitis (inflammation of the nasopharynx)
Fistula (an abnormal connection or passageway between two)
Drug hypersensitivity
Drug ineffective
Dyspnoea (difficult or laboured respiration)
Ear infection
Erythema (redness of the skin)
Eye irritation
Fatigue (feeling of tiredness)
Headache (pain in head)

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 15 people, 18.99%
Primary Immunodeficiency Syndrome: 11 people, 13.92%
Immune System Disorder: 10 people, 12.66%
Immunodeficiency: 9 people, 11.39%
Fabry's Disease (build up of a particular type of fat, called globotriaosylceramide, in the body's cells): 7 people, 8.86%
Nausea (feeling of having an urge to vomit): 6 people, 7.59%
Vitamin B12 Deficiency: 5 people, 6.33%
Migraine Without Aura (headache without neurological problems): 4 people, 5.06%
Functional Gastrointestinal Disorder (functional problem in separate organs of gastrointestinal system): 4 people, 5.06%
Diabetes: 4 people, 5.06%

* Approximation only. Some reports may have incomplete information.

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