Glimepiride and Extrapyramidal disorder - a phase IV clinical study of FDA data

Summary:

Extrapyramidal disorder is reported as a side effect among people who take Glimepiride (glimepiride), especially for people who are male, 60+ old, also take Amlodipine, and have High blood pressure.

The phase IV clinical study analyzes which people have Extrapyramidal disorder when taking Glimepiride. It is created by eHealthMe based on reports of 45,086 people who have side effects when taking Glimepiride from the FDA, and is updated regularly.

What is Glimepiride?

Glimepiride has active ingredients of glimepiride. It is often used in diabetes. eHealthMe is studying from 45,909 Glimepiride users. Check the latest studies of Glimepiride.

What is Extrapyramidal disorder?

Extrapyramidal disorder (involuntary muscle spasms in the face and neck) is found to be associated with 813 drugs and 960 conditions by eHealthMe. Check the latest studies of Extrapyramidal disorder.



On Jul, 14, 2026

45,086 people reported to have side effects when taking Glimepiride.
Among them, 67 people (0.15%) have Extrapyramidal disorder.

Could Glimepiride cause Extrapyramidal disorder?

Among these 67 people:

What is the gender of people who have Extrapyramidal disorder when taking Glimepiride? *

  • female: 43.55 %
  • male: 56.45 %

What is the age of people who have Extrapyramidal disorder when taking Glimepiride? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 3.57 %
  • 50-59: 3.57 %
  • 60+: 92.86 %

What are other drugs people take besides Glimepiride? *

  1. Amlodipine: 26 people, 38.81%
  2. Diclofenac: 20 people, 29.85%
  3. Acetylsalicylic Acid: 18 people, 26.87%
  4. Aspirin: 14 people, 20.90%
  5. Januvia: 13 people, 19.40%
  6. Depakote: 13 people, 19.40%
  7. Metformin: 10 people, 14.93%
  8. Gaviscon: 8 people, 11.94%
  9. Metoclopramide: 8 people, 11.94%
  10. Simvastatin: 7 people, 10.45%

What are other side effects people have besides Extrapyramidal disorder? *

  1. Pancreatitis Acute (sudden inflammation of pancreas): 19 people, 28.36%
  2. Tremor (trembling or shaking movements in one or more parts of your body): 19 people, 28.36%
  3. Fall: 17 people, 25.37%
  4. Fatigue (feeling of tiredness): 14 people, 20.90%
  5. Abdominal Pain Upper: 13 people, 19.40%
  6. Nausea And Vomiting: 13 people, 19.40%
  7. Hyperhidrosis (abnormally increased sweating): 11 people, 16.42%
  8. Gait Disturbance: 10 people, 14.93%
  9. Torticollis (a twisted neck in which the head is tipped to one side, while the chin is turned to the other): 9 people, 13.43%
  10. Drug Level Increased: 9 people, 13.43%

What are the existing conditions these people have? *

  1. High Blood Pressure: 26 people, 38.81%
  2. Back Pain: 21 people, 31.34%
  3. Parkinson's Disease: 19 people, 28.36%
  4. Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 13 people, 19.40%
  5. Osteoporosis (bones weak and more likely to break): 12 people, 17.91%
  6. Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 12 people, 17.91%
  7. Atherosclerosis (disorder of the arteries): 10 people, 14.93%
  8. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 9 people, 13.43%
  9. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 4.48%
  10. Carotid Arteriosclerosis (plaque deposition in artery): 2 people, 2.99%

* Approximation only. Some reports may have incomplete information.

Do you take Glimepiride and have Extrapyramidal disorder?

- Check whether Extrapyramidal disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Glimepiride:

Extrapyramidal disorder treatments and more:

How severe was Extrapyramidal disorder and when was it recovered:

Expand to all the drugs that have ingredients of glimepiride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Glimepiride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Extrapyramidal disorder:

Browse all the conditions that are associated with Extrapyramidal disorder:


How the study uses the data?

The study uses data from the FDA. It is based on glimepiride (the active ingredients of Glimepiride) and Glimepiride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: