Hydramine and Saizen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hydramine (diphenhydramine hydrochloride) and Saizen (somatropin recombinant). Common drug interactions include erythema among females and ear infection among males.

The phase IV clinical study analyzes what interactions people have when they take Hydramine and Saizen. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Hydramine?

Hydramine has active ingredients of diphenhydramine hydrochloride. It is often used in insomnia. eHealthMe is studying from 114,900 Hydramine users. Check the latest studies of Hydramine.

What is Saizen?

Saizen has active ingredients of somatropin recombinant. eHealthMe is studying from 3,122 Saizen users. Check the latest studies of Saizen.

On Jul, 20, 2026

17 people who take Hydramine and Saizen together, and have interactions are studied.

What are the common drug interactions of Hydramine and Saizen, by gender? *:

female:

Erythema (redness of the skin)
Herpes zoster
Infection
Lyme disease (a bacterial infection that is spread to humans by infected ticks)
Psoriasis (immune-mediated disease that affects the skin)
Skin infection
Mastitis (inflammation of breast)
Ear infection
Infusion site swelling
Pituitary tumour

male:

Ear infection
Nasopharyngitis (inflammation of the nasopharynx)
Headache (pain in head)
Lethargy (tiredness)
Skin irritation
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Hypothalamo-pituitary disorders (loss of function in an endocrine gland due to failure of the pituitary gland to secrete hormones which stimulate that gland's function)
Thermal burns of eye (burn of eye by heat)
Nephritic syndrome (a collection of signs (known as a syndrome) associated with disorders affecting the kidneys, more specifically glomerular disorders)
Haemorrhage (bleeding)

What are the common drug interactions of Hydramine and Saizen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Nephritic syndrome (a collection of signs (known as a syndrome) associated with disorders affecting the kidneys, more specifically glomerular disorders)

20-29:

n/a

30-39:

Abdominal pain
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cyst (a closed sac)
Ear infection
Eye infection
Haemorrhage (bleeding)
Headache (pain in head)
Lethargy (tiredness)
Nasopharyngitis (inflammation of the nasopharynx)
Pruritus (severe itching of the skin)

40-49:

n/a

50-59:

Pituitary tumour
Psoriasis (immune-mediated disease that affects the skin)
Skin infection
Injection site erythema (redness at injection site)
Injection site swelling
Sinusitis (inflammation of sinus)
Localised infection (infection at the single location)
Cellulitis (infection under the skin)
Influenza
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)

60+:

Hypothalamo-pituitary disorders (loss of function in an endocrine gland due to failure of the pituitary gland to secrete hormones which stimulate that gland's function)
Cyst (a closed sac)
Pituitary tumour

What are the existing conditions these people have? *

Growth Hormone Deficiency: 10 people, 58.82%
Hypopituitarism (diminished hormone secretion by the pituitary gland, causing dwarfism in children and premature aging in adults): 9 people, 52.94%
Immune System Disorder: 6 people, 35.29%
Immunodeficiency Common Variable: 5 people, 29.41%
Hypergammaglobulinaemia (elevated levels of gamma globulin): 2 people, 11.76%
Type 1 Diabetes: 1 person, 5.88%
Rickets (softening of bones): 1 person, 5.88%
High Blood Pressure: 1 person, 5.88%
Diabetes: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

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