Hydramine and Synagis drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hydramine (diphenhydramine hydrochloride) and Synagis (palivizumab). Common drug interactions include rash among females and febrile neutropenia among males.

The phase IV clinical study analyzes what interactions people have when they take Hydramine and Synagis. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Hydramine?

Hydramine has active ingredients of diphenhydramine hydrochloride. It is often used in insomnia. eHealthMe is studying from 114,900 Hydramine users. Check the latest studies of Hydramine.

What is Synagis?

Synagis has active ingredients of palivizumab. eHealthMe is studying from 19,114 Synagis users. Check the latest studies of Synagis.

On Jul, 17, 2026

26 people who take Hydramine and Synagis together, and have interactions are studied.

Hydramine and Synagis drug interactions.

What are the common drug interactions of Hydramine and Synagis, by gender? *:

female:

Rash
Pyrexia (fever)
Human rhinovirus test positive
Apnoea (suspension of external breathing)
Cardiac arrest
Cardiac hypertrophy (thickening of the heart muscle)
Febrile neutropenia (fever with reduced white blood cells)
Infection
Malaise (a feeling of general discomfort or uneasiness)
Metapneumovirus infection (infection with human metapneumovirus)

male:

Febrile neutropenia (fever with reduced white blood cells)
Pain
Bone marrow failure
Feeding disorder (when children refuse to eat certain food groups)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Mucosal inflammation (infection of mucous membrane)
Portal vein thrombosis (venous thrombosis affecting the hepatic portal vein)
Pulmonary haemorrhage (acute bleeding from the lung)
Venoocclusive liver disease (small veins in the liver are obstructed)
Constipation

What are the common drug interactions of Hydramine and Synagis, by age (0-1 to 60+)? *:

0-1:

Rash
Febrile neutropenia (fever with reduced white blood cells)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Penile ulceration
Feeding disorder (when children refuse to eat certain food groups)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Mucosal inflammation (infection of mucous membrane)
Portal vein thrombosis (venous thrombosis affecting the hepatic portal vein)
Pulmonary haemorrhage (acute bleeding from the lung)
Venoocclusive liver disease (small veins in the liver are obstructed)

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Thymus Enlargement: 3 people, 11.54%
Neuroblastoma (a cancer that forms in your nerve tissue): 3 people, 11.54%
Cardiac Failure: 3 people, 11.54%
Premature Baby: 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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