Hydrochlorothiazide and Cayston drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Hydrochlorothiazide (hydrochlorothiazide) and Cayston (aztreonam). Common drug interactions include insomnia among females and ventricular pre-excitation among males.
The phase IV clinical study analyzes what interactions people have when they take Hydrochlorothiazide and Cayston. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.
What is Hydrochlorothiazide?
Hydrochlorothiazide has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 182,194 Hydrochlorothiazide users. Check the latest studies of Hydrochlorothiazide.
What is Cayston?
Cayston has active ingredients of aztreonam. It is often used in cystic fibrosis. eHealthMe is studying from 5,310 Cayston users. Check the latest studies of Cayston.
44 people who take Hydrochlorothiazide and Cayston together, and have interactions are studied.

What are the common drug interactions of Hydrochlorothiazide and Cayston, by gender? *:
female:
- Insomnia (sleeplessness)
- Fatigue (feeling of tiredness)
- Abdominal pain upper
- Ageusia (loss of taste functions of the tongue)
- Chest discomfort
- Dyspnoea (difficult or laboured respiration)
- Headache (pain in head)
- Hypersensitivity
- Hypoglycaemia (deficiency of glucose in the bloodstream)
- Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
male:
- Ventricular pre-excitation
- Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
- Drug rash with eosinophilia and systemic symptoms (adverse drug reactions with rash)
- Dyspnoea (difficult or laboured respiration)
- Hypersensitivity
- Lip swelling
- Lung transplant
- Nasopharyngitis (inflammation of the nasopharynx)
- Pruritus (severe itching of the skin)
- Throat tightness
What are the common drug interactions of Hydrochlorothiazide and Cayston, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Infection
- Productive cough
30-39:
- Hospitalisation
- Respiratory syncytial virus infection (viral disease of respiratory system)
40-49:
- Influenza
- Pneumonia
- Sepsis (a severe blood infection that can lead to organ failure and death)
50-59:
- Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
- Thrombocytopenia (decrease of platelets in blood)
- Leukocytosis (increased white blood cells)
- Eosinophilia (eosinophil count in the peripheral blood exceeds)
- Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
60+:
- Ventricular pre-excitation
- Insomnia (sleeplessness)
- Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
- Respiratory tract congestion (blockage on respiratory system)
- Sinus headache (headache caused by sinus infections)
- Sinusitis (inflammation of sinus)
- Upper-airway cough syndrome
- Disturbance in attention
- Body temperature increased
- Drug rash with eosinophilia and systemic symptoms (adverse drug reactions with rash)
What are the existing conditions these people have? *
- Sedation: 25 people, 56.82%
- Type 2 Diabetes: 21 people, 47.73%
- Seizures (abnormal excessive or synchronous neuronal activity in the brain): 21 people, 47.73%
- Diabetes: 5 people, 11.36%
- Cystic Fibrosis Lung (fibrosis with cyst in the lung): 3 people, 6.82%
- Cough: 3 people, 6.82%
* Approximation only. Some reports may have incomplete information.
Do you take Hydrochlorothiazide and Cayston?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Hydrochlorothiazide (182,194 reports)
- Cayston (5,310 reports)
Browse all drug interactions of Hydrochlorothiazide and Cayston:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Hydrochlorothiazide:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Cayston:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Hydrochlorothiazide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cayston and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on hydrochlorothiazide and aztreonam (the active ingredients of Hydrochlorothiazide and Cayston, respectively), and Hydrochlorothiazide and Cayston (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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