Hydrochlorothiazide and Sodium ascorbate drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Hydrochlorothiazide (hydrochlorothiazide) and Sodium ascorbate (vitamin c (ascorbic acid)). Common drug interactions include dyspepsia among females and mania among males.
The phase IV clinical study analyzes what interactions people have when they take Hydrochlorothiazide and Sodium ascorbate. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.
What is Hydrochlorothiazide?
Hydrochlorothiazide has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 182,194 Hydrochlorothiazide users. Check the latest studies of Hydrochlorothiazide.
What is Sodium ascorbate?
Sodium ascorbate has active ingredients of vitamin c (ascorbic acid). eHealthMe is studying from 321 Sodium ascorbate users. Check the latest studies of Sodium ascorbate.
25 people who take Hydrochlorothiazide and Sodium ascorbate together, and have interactions are studied.

What are the common drug interactions of Hydrochlorothiazide and Sodium Ascorbate, by gender? *:
female:
- Dyspepsia (indigestion)
- Infusion related reaction
- Macular degeneration (painless eye condition that leads to the gradual loss of central vision)
- Malaise (a feeling of general discomfort or uneasiness)
- Nausea (feeling of having an urge to vomit)
- Pain
- Paraesthesia oral (sensation of tingling, tickling, prickling, pricking, or burning of a person's oral with no apparent long-term physical effect)
- Procedural pain
- Pyrexia (fever)
- Weight decreased
male:
- Mania (a state of abnormally elevated or irritable mood)
- Decreased appetite
- Dehydration (dryness resulting from the removal of water)
- Diarrhoea
- Red blood cell count decreased
- Weight decreased
- White blood cell count decreased
What are the common drug interactions of Hydrochlorothiazide and Sodium Ascorbate, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Dysphonia (speech disorder attributable to a disorder of phonation)
- Pruritus (severe itching of the skin)
- Seasonal allergy (allergic condition due to certain season)
60+:
- Weight decreased
- Abdominal pain
- Paraesthesia oral (sensation of tingling, tickling, prickling, pricking, or burning of a person's oral with no apparent long-term physical effect)
- Procedural pain
- Pyrexia (fever)
- Constipation
- Anaemia (lack of blood)
- Colitis (inflammation of colon)
- Colitis ulcerative (inflammation of colon with ulcer)
- Erythema (redness of the skin)
What are the existing conditions these people have? *
- Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 14 people, 56.00%
- Allergies: 13 people, 52.00%
- Asthma: 12 people, 48.00%
- Nausea (feeling of having an urge to vomit): 9 people, 36.00%
- Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 5 people, 20.00%
- Multiple Myeloma (cancer of the plasma cells): 3 people, 12.00%
- Pain: 2 people, 8.00%
* Approximation only. Some reports may have incomplete information.
Do you take Hydrochlorothiazide and Sodium ascorbate?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Hydrochlorothiazide (182,194 reports)
- Sodium ascorbate (321 reports)
Browse all drug interactions of Hydrochlorothiazide and Sodium ascorbate:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Hydrochlorothiazide:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Sodium ascorbate:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Hydrochlorothiazide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Sodium ascorbate and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on hydrochlorothiazide and vitamin c (ascorbic acid) (the active ingredients of Hydrochlorothiazide and Sodium ascorbate, respectively), and Hydrochlorothiazide and Sodium ascorbate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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