Hydrocodone and Reyataz drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hydrocodone (hydrocodone bitartrate; ibuprofen) and Reyataz (atazanavir sulfate). Common drug interactions include blood creatinine increased among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Hydrocodone and Reyataz. It is created by eHealthMe based on reports of 56 people who take the same drugs from the FDA, and is updated regularly.

What is Hydrocodone?

Hydrocodone has active ingredients of hydrocodone bitartrate; ibuprofen. eHealthMe is studying from 13,115 Hydrocodone users. Check the latest studies of Hydrocodone.

What is Reyataz?

Reyataz has active ingredients of atazanavir sulfate. It is often used in hiv infection. eHealthMe is studying from 11,386 Reyataz users. Check the latest studies of Reyataz.

On Jul, 19, 2026

56 people who take Hydrocodone and Reyataz together, and have interactions are studied.

Hydrocodone and Reyataz drug interactions.

What are the common drug interactions of Hydrocodone and Reyataz, by gender? *:

female:

Blood creatinine increased
Blood potassium decreased
Enamel anomaly
Glomerular filtration rate decreased
Hip fracture
Hypertension (high blood pressure)
Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
Lower limb fracture
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Nephropathy (damage to or disease of a kidney)

male:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)
Back pain
Dysstasia (difficulty in standing)
Fatigue (feeling of tiredness)
Spinal compression fracture (fracture due to spinal compression on bone)
Asthenia (weakness)
Insomnia (sleeplessness)

What are the common drug interactions of Hydrocodone and Reyataz, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Chronic kidney disease
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Pain
Renal failure (kidney dysfunction)
Depression
Insomnia (sleeplessness)
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Renal injury (kidney injury)

40-49:

Pain
Bone density decreased
Renal failure (kidney dysfunction)
Anaemia (lack of blood)
Depression
Osteoporosis (bones weak and more likely to break)
Renal impairment (severely reduced kidney function)
Ankle fracture
Hyperkalaemia (damage to or disease of the kidney)
Hypertension (high blood pressure)

50-59:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Pain
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Bone density decreased
Gait disturbance
Chronic kidney disease
Depression

60+:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Insomnia (sleeplessness)
Nephrolithiasis (calculi in the kidneys)
Renal impairment (severely reduced kidney function)
Tendon rupture (tear of tendon)
Upper limb fracture
Bone loss
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)

What are the existing conditions these people have? *

Pain: 10 people, 17.86%
Stress And Anxiety: 7 people, 12.50%
Bacterial Infection: 7 people, 12.50%
High Blood Pressure: 7 people, 12.50%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 12.50%
Nausea (feeling of having an urge to vomit): 6 people, 10.71%
Depression: 6 people, 10.71%
Inflammation: 5 people, 8.93%
Fungal Infection: 5 people, 8.93%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 4 people, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Hydrocodone and Reyataz?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously