Hydrocortisone and Tysabri drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hydrocortisone (hydrocortisone) and Tysabri (natalizumab). Common drug interactions include cough among females and progressive multifocal leukoencephalopathy among males.

The phase IV clinical study analyzes what interactions people have when they take Hydrocortisone and Tysabri. It is created by eHealthMe based on reports of 71 people who take the same drugs from the FDA, and is updated regularly.

What is Hydrocortisone?

Hydrocortisone has active ingredients of hydrocortisone. It is often used in addison's disease. eHealthMe is studying from 40,425 Hydrocortisone users. Check the latest studies of Hydrocortisone.

What is Tysabri?

Tysabri has active ingredients of natalizumab. It is often used in multiple sclerosis. eHealthMe is studying from 221,369 Tysabri users. Check the latest studies of Tysabri.



On Jul, 12, 2026

71 people who take Hydrocortisone and Tysabri together, and have interactions are studied.

Hydrocortisone and Tysabri drug interactions.

What are the common drug interactions of Hydrocortisone and Tysabri, by gender? *:

female:

  1. Cough
  2. Diarrhoea
  3. Headache (pain in head)
  4. Migraine (headache)
  5. Muscle spasms (muscle contraction)
  6. Abdominal discomfort
  7. Amenorrhoea (absence of a menstrual period in a woman of reproductive age)
  8. Blood pressure diastolic increased
  9. Contusion (a type of hematoma of tissue in which capillaries)
  10. Depression

male:

  1. Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells)
  2. Anxiety
  3. Back pain
  4. Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
  5. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  6. Depression
  7. Fatigue (feeling of tiredness)
  8. Joint swelling
  9. Loss of consciousness
  10. Nausea (feeling of having an urge to vomit)

What are the common drug interactions of Hydrocortisone and Tysabri, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Cholecystitis chronic (long lasting infection of gallbladder)
  4. Colon cancer
  5. Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
  6. Deformity (disfigurement)
  7. Gallbladder disorder
  8. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  9. Injury
  10. Pain

20-29:

  1. Hyperglycaemia (high blood sugar)
  2. Influenza
  3. Sepsis (a severe blood infection that can lead to organ failure and death)
  4. Rhinovirus infection
  5. Bradyphrenia (neurological term referring to the slowness of thought common to many disorders of the brain)
  6. Burning sensation
  7. Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
  8. Confusional state
  9. Memory impairment
  10. Pain in extremity

30-39:

  1. Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells)
  2. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  3. Anxiety
  4. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  5. Depression
  6. Fungal infection
  7. Immune reconstitution syndrome (immune recovery syndrome)
  8. Pregnancy
  9. Rash
  10. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)

40-49:

  1. Fall
  2. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  3. Back pain
  4. Fatigue (feeling of tiredness)
  5. Diarrhoea
  6. Nasopharyngitis (inflammation of the nasopharynx)
  7. Pain
  8. Abdominal discomfort
  9. Amenorrhoea (absence of a menstrual period in a woman of reproductive age)
  10. Blood pressure diastolic increased

50-59:

  1. Cardiac murmur (an heart sound in valve abnormality)
  2. Developmental delay
  3. Emotional disorder
  4. Hypertelorism of orbit (abnormally increased distance between two organs or bodily parts, usually referring to an increased distance between the orbits (eyes)--orbital hypertelorism)
  5. Abasia (inability to walk)
  6. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  7. Electrolyte imbalance
  8. Gait disturbance
  9. Mobility decreased (ability to move is reduced)
  10. Cheilitis (infection of lips)

60+:

  1. Haematuria (presence of blood in urine)
  2. Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
  3. Dysarthria (speech disorder)
  4. Enterobacter sepsis (sepsis due to bacteria of the family enterobacteriaceae)
  5. Gait disturbance
  6. Headache (pain in head)
  7. Hypertension (high blood pressure)
  8. Hypoaesthesia (reduced sense of touch or sensation)
  9. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
  10. Nausea (feeling of having an urge to vomit)

What are the existing conditions these people have? *

  1. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 17 people, 23.94%
  2. Fatigue (feeling of tiredness): 7 people, 9.86%
  3. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 9.86%
  4. Pain: 6 people, 8.45%
  5. Enlarged Prostate: 5 people, 7.04%
  6. High Blood Pressure: 5 people, 7.04%
  7. Viral Infection: 4 people, 5.63%
  8. Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 4 people, 5.63%
  9. Constipation: 4 people, 5.63%
  10. Depression: 4 people, 5.63%

* Approximation only. Some reports may have incomplete information.

Do you take Hydrocortisone and Tysabri?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Hydrocortisone and Tysabri:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Hydrocortisone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Tysabri:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hydrocortisone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tysabri and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on hydrocortisone and natalizumab (the active ingredients of Hydrocortisone and Tysabri, respectively), and Hydrocortisone and Tysabri (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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