Hydrodiuril and Sinemet drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hydrodiuril (hydrochlorothiazide) and Sinemet (carbidopa; levodopa). Common drug interactions include hallucination among females and cerebral haemorrhage among males.

The phase IV clinical study analyzes what interactions people have when they take Hydrodiuril and Sinemet. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Hydrodiuril?

Hydrodiuril has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 4,211 Hydrodiuril users. Check the latest studies of Hydrodiuril.

What is Sinemet?

Sinemet has active ingredients of carbidopa; levodopa. It is often used in parkinson's disease. eHealthMe is studying from 29,601 Sinemet users. Check the latest studies of Sinemet.

On Jul, 15, 2026

26 people who take Hydrodiuril and Sinemet together, and have interactions are studied.

Hydrodiuril and Sinemet drug interactions.

What are the common drug interactions of Hydrodiuril and Sinemet, by gender? *:

female:

Hallucination (an experience involving the perception of something not present)
Dizziness
Asthenia (weakness)
Blood potassium decreased
Cystitis (inflammation of the wall of the bladder)
Diarrhoea
Haemoglobin decreased
Hallucination, visual (seeing things that aren't there)
Nausea (feeling of having an urge to vomit)
Overdose

male:

Cerebral haemorrhage (bleeding within the brain)
Death
Confusional state
Diarrhoea
Hallucination (an experience involving the perception of something not present)
Immunodeficiency
Insomnia (sleeplessness)
Overdose
Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
Pneumonia

What are the common drug interactions of Hydrodiuril and Sinemet, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Completed suicide (act of taking one's own life)
Overdose

30-39:

n/a

40-49:

n/a

50-59:

Blepharitis (chronic inflammation of the eyelid)
Blood creatine phosphokinase increased
Muscle spasms (muscle contraction)
Myositis (inflammation of the muscles)
Peripheral neuropathy (damage to nerves of the peripheral nervous system)
Sensory disturbance (sense disturbance)

60+:

Hallucination (an experience involving the perception of something not present)
Diarrhoea
Overdose
Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal)
Throat tightness
Urinary tract infection
Dysarthria (speech disorder)
Haemoglobin decreased
Lethargy (tiredness)
White blood cell count decreased

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 7 people, 26.92%
Hallucinations (sensations that appear real but are created by your mind): 6 people, 23.08%
Delusion (a false belief or opinion): 6 people, 23.08%
Pain: 4 people, 15.38%
Rosacea (a skin condition that causes facial redness): 3 people, 11.54%
Infection: 3 people, 11.54%
Hypoglycemia (low blood sugar): 3 people, 11.54%
Red Blood Cell Count Abnormal: 2 people, 7.69%
Joint Pain: 2 people, 7.69%
Indigestion: 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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