Hydroxocobalamin and Cyclophosphamide drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Hydroxocobalamin (hydroxocobalamin) and Cyclophosphamide (cyclophosphamide). Common drug interactions include hepatic failure among females and diarrhoea among males.
The phase IV clinical study analyzes what interactions people have when they take Hydroxocobalamin and Cyclophosphamide. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.
What is Hydroxocobalamin?
Hydroxocobalamin has active ingredients of hydroxocobalamin. It is often used in pernicious anaemia. eHealthMe is studying from 4,273 Hydroxocobalamin users. Check the latest studies of Hydroxocobalamin.
What is Cyclophosphamide?
Cyclophosphamide has active ingredients of cyclophosphamide. It is often used in multiple myeloma. eHealthMe is studying from 185,240 Cyclophosphamide users. Check the latest studies of Cyclophosphamide.
21 people who take Hydroxocobalamin and Cyclophosphamide together, and have interactions are studied.

What are the common drug interactions of Hydroxocobalamin and Cyclophosphamide, by gender? *:
female:
- Hepatic failure (liver failure)
- Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Constipation
- Lower respiratory tract infection
- Neutropenic sepsis (whole body infection is caused by a condition in which the number of white blood cells (called neutrophils) in the blood is low. neutrophils help the body to fight infection)
- Antibiotic therapy
- Aphasia (damage to the parts of the brain that control language)
- Autonomic neuropathy (malfunction of the autonomic nervous system (ans))
- Blood lactic acid increased
male:
- Diarrhoea
- Ileus (a painful obstruction of the ileum or other part of the intestine)
- Squamous cell carcinoma (a cancer of a kind of epithelial cell)
- Constipation
- Dehydration (dryness resulting from the removal of water)
- Nausea (feeling of having an urge to vomit)
- Vomiting
- Abdominal pain
- Haematotoxicity (toxins that destroy red blood cells)
- Neuropathy peripheral (surface nerve damage)
What are the common drug interactions of Hydroxocobalamin and Cyclophosphamide, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Antibiotic therapy
- Aphasia (damage to the parts of the brain that control language)
- Blood lactic acid increased
- Blood pressure increased
- Chills (felling of cold)
- Csf lactate increased
- Hypersomnia (excessive daytime sleepiness (eds))
- Mobility decreased (ability to move is reduced)
- Nausea (feeling of having an urge to vomit)
- Neutropenia (an abnormally low number of neutrophils)
20-29:
- Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
30-39:
n/a
40-49:
n/a
50-59:
n/a
60+:
- Diarrhoea
- Constipation
- Lower respiratory tract infection
- Neutropenic sepsis (whole body infection is caused by a condition in which the number of white blood cells (called neutrophils) in the blood is low. neutrophils help the body to fight infection)
- Autonomic neuropathy (malfunction of the autonomic nervous system (ans))
- Febrile neutropenia (fever with reduced white blood cells)
- Haematotoxicity (toxins that destroy red blood cells)
- Neutropenia (an abnormally low number of neutrophils)
- Pulmonary embolism (blockage of the main artery of the lung)
- Squamous cell carcinoma (a cancer of a kind of epithelial cell)
What are the existing conditions these people have? *
- Amyloidosis (a tumour within which amyloid is produced): 6 people, 28.57%
- Primary Amyloidosis (disease that occurs when substances called amyloid proteins build up in your organs): 5 people, 23.81%
- Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 4 people, 19.05%
- Nausea (feeling of having an urge to vomit): 3 people, 14.29%
- Vitamin B12 Deficiency: 2 people, 9.52%
- Rickets (softening of bones): 2 people, 9.52%
- Oral Candidiasis (fungal infection of mouth): 2 people, 9.52%
- Hypokalemia (low potassium): 2 people, 9.52%
- High Blood Pressure: 2 people, 9.52%
- Breast Cancer: 2 people, 9.52%
* Approximation only. Some reports may have incomplete information.
Do you take Hydroxocobalamin and Cyclophosphamide?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Hydroxocobalamin (4,273 reports)
- Cyclophosphamide (185,240 reports)
Browse all drug interactions of Hydroxocobalamin and Cyclophosphamide:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Hydroxocobalamin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Cyclophosphamide:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Hydroxocobalamin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cyclophosphamide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Hu P, Lu L, Hu B, Deng F, Fei WJ, "Cyclophosphamide‐Induced Hypertensive Encephalopathy in a Young Girl With Lupus", The Journal of Clinical Hypertension, 2012 Apr .
- Hu P, Lu L, Hu B, Deng F, Fei WJ, "Cyclophosphamide‐Induced Hypertensive Encephalopathy in a Young Girl With Lupus", The Journal of Clinical Hypertension, 2012 Apr .
How the study uses the data?
The study uses data from the FDA. It is based on hydroxocobalamin and cyclophosphamide (the active ingredients of Hydroxocobalamin and Cyclophosphamide, respectively), and Hydroxocobalamin and Cyclophosphamide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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