Hydroxyurea and Cresemba drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hydroxyurea (hydroxyurea) and Cresemba (isavuconazonium sulfate). Common drug interactions include death among females and bacteraemia among males.

The phase IV clinical study analyzes what interactions people have when they take Hydroxyurea and Cresemba. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Hydroxyurea?

Hydroxyurea has active ingredients of hydroxyurea. It is often used in polycythemia vera. eHealthMe is studying from 17,240 Hydroxyurea users. Check the latest studies of Hydroxyurea.

What is Cresemba?

Cresemba has active ingredients of isavuconazonium sulfate. eHealthMe is studying from 2,574 Cresemba users. Check the latest studies of Cresemba.



On Jul, 12, 2026

24 people who take Hydroxyurea and Cresemba together, and have interactions are studied.

Hydroxyurea and Cresemba drug interactions.

What are the common drug interactions of Hydroxyurea and Cresemba, by gender? *:

female:

  1. Death
  2. Lung infection
  3. Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
  4. Fall
  5. Feeding disorder (when children refuse to eat certain food groups)
  6. Joint dislocation (a joint position is changed from normal position)
  7. Nausea (feeling of having an urge to vomit)
  8. Sleep disorder

male:

  1. Bacteraemia (presence of bacteria in the blood)
  2. Decreased appetite
  3. Aspergillus test positive
  4. Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
  5. C-reactive protein increased
  6. Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
  7. Cerebral atrophy (decrement in size of brain)
  8. Cerebral ventricle dilatation (enlargement of ventricle of brain)
  9. Confusional state
  10. Cough

What are the common drug interactions of Hydroxyurea and Cresemba, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
  2. Mitral valve disease (disease of mitral valve of heart)
  3. Neuropathy peripheral (surface nerve damage)
  4. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  5. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  6. Pleural effusion (water on the lungs)
  7. Pneumonia fungal
  8. Pyrexia (fever)
  9. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  10. Skin hyperpigmentation (disorders affect the colour of your skin)

20-29:

  1. Aplasia (defective development or congenital absence of an organ or tissue)
  2. Bacteraemia (presence of bacteria in the blood)
  3. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  4. Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
  5. Escherichia bacteraemia (presence of bacteria escherichia coli in the blood)
  6. Hyperglycaemia (high blood sugar)
  7. Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
  8. Tumour lysis syndrome (a group of metabolic complications that can occur after treatment of cancer, these complications are caused by the breakdown products of dying cancer cells)

30-39:

n/a

40-49:

n/a

50-59:

  1. Abscess oral (abscess in the mouth)
  2. Acute respiratory distress syndrome
  3. Arthralgia (joint pain)
  4. Bacterial sepsis
  5. Cardiac failure congestive
  6. Dyspnoea (difficult or laboured respiration)
  7. Haemoglobin decreased
  8. Hypotension (abnormally low blood pressure)
  9. Impaired healing
  10. Mobility decreased (ability to move is reduced)

60+:

  1. Lung infection
  2. Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
  3. Bacteraemia (presence of bacteria in the blood)
  4. Cardiac arrest
  5. Chills (felling of cold)
  6. Constipation
  7. Deafness
  8. Depressed mood
  9. Diarrhoea
  10. Disturbance in attention

What are the existing conditions these people have? *

  1. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 14 people, 58.33%
  2. Primary Myelofibrosis (primary disorder of the bone marrow): 5 people, 20.83%
  3. High Blood Pressure: 5 people, 20.83%
  4. Pain: 4 people, 16.67%
  5. Nausea And Vomiting: 3 people, 12.50%
  6. Nausea (feeling of having an urge to vomit): 3 people, 12.50%
  7. Hypokalemia (low potassium): 3 people, 12.50%
  8. Tumor Lysis Syndrome: 2 people, 8.33%
  9. Tumor: 2 people, 8.33%
  10. Pneumonia: 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Hydroxyurea and Cresemba?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Hydroxyurea and Cresemba:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Hydroxyurea:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Cresemba:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hydroxyurea and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cresemba and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on hydroxyurea and isavuconazonium sulfate (the active ingredients of Hydroxyurea and Cresemba, respectively), and Hydroxyurea and Cresemba (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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