Hydroxyurea and Vancomycin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Hydroxyurea (hydroxyurea) and Vancomycin (vancomycin). Common drug interactions include neutropenia among females and staphylococcal infection among males.
The phase IV clinical study analyzes what interactions people have when they take Hydroxyurea and Vancomycin. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.
What is Hydroxyurea?
Hydroxyurea has active ingredients of hydroxyurea. It is often used in polycythemia vera. eHealthMe is studying from 17,240 Hydroxyurea users. Check the latest studies of Hydroxyurea.
What is Vancomycin?
Vancomycin has active ingredients of vancomycin. eHealthMe is studying from 17,165 Vancomycin users. Check the latest studies of Vancomycin.
44 people who take Hydroxyurea and Vancomycin together, and have interactions are studied.

What are the common drug interactions of Hydroxyurea and Vancomycin, by gender? *:
female:
- Neutropenia (an abnormally low number of neutrophils)
- Thrombocytopenia (decrease of platelets in blood)
- Leukopenia (less number of white blood cells in blood)
- Anaemia (lack of blood)
- Escherichia sepsis (bacterial infection by escherichia coli)
- Febrile bone marrow aplasia (bone marrow greatly decreases or stops production of blood cells)
- Fungal sepsis (whole body infection by fungus)
- Disease progression
- Fall
- Febrile neutropenia (fever with reduced white blood cells)
male:
- Staphylococcal infection (an infection with staphylococcus bacteria)
- Septic shock (shock due to blood infection)
- Pericarditis (inflammation of the pericardium)
- Enterocolitis bacterial
- Acute respiratory failure
- Anaemia (lack of blood)
- Arthralgia (joint pain)
- Blood lactate dehydrogenase increased
- Chills (felling of cold)
- Coombs positive haemolytic anaemia
What are the common drug interactions of Hydroxyurea and Vancomycin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- Fungaemia (fungi circulate in the blood)
- Neutropenia (an abnormally low number of neutrophils)
10-19:
- Anaemia (lack of blood)
- Arthralgia (joint pain)
- Blood lactate dehydrogenase increased
- Chills (felling of cold)
- Coombs positive haemolytic anaemia
- General physical health deterioration (weak health status)
- Haemoglobin decreased
- Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid)
- Reticulocyte count increased
20-29:
- Drug ineffective
- Endocarditis (inflammation in heart muscle)
30-39:
- Drug ineffective
- Mucosal inflammation (infection of mucous membrane)
40-49:
- Angiokeratoma (a skin disease in which warty growths occur in groups, together with epidermal thickening)
- Leukopenia (less number of white blood cells in blood)
- Skin disorder (skin disease)
- Skin mass
- Febrile neutropenia (fever with reduced white blood cells)
- Palmar erythema (reddening of the palms at the thenar and hypothenar eminences)
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
- Purpura (purplish discoloration of the skin)
50-59:
- Febrile neutropenia (fever with reduced white blood cells)
- Drug ineffective
- Neutropenia (an abnormally low number of neutrophils)
- Hepatic failure (liver failure)
- Neutropenic sepsis (whole body infection is caused by a condition in which the number of white blood cells (called neutrophils) in the blood is low. neutrophils help the body to fight infection)
60+:
- Neutropenia (an abnormally low number of neutrophils)
- Thrombocytopenia (decrease of platelets in blood)
- Pneumatosis (air or gas in an abnormal location in the body)
- Respiratory distress (difficulty in breathing)
- Febrile neutropenia (fever with reduced white blood cells)
- Fungal sepsis (whole body infection by fungus)
- Disease progression
- Fall
- Electrocardiogram qt prolonged
- Pericarditis (inflammation of the pericardium)
What are the existing conditions these people have? *
- Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 21 people, 47.73%
- Septic Shock (shock due to blood infection): 8 people, 18.18%
- Insomnia (sleeplessness): 7 people, 15.91%
- White Blood Cell Count Increased: 6 people, 13.64%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 13.64%
- Back Pain: 6 people, 13.64%
- Constipation: 6 people, 13.64%
- Type 2 Diabetes: 6 people, 13.64%
- Acute Leukaemia (blood cancer): 6 people, 13.64%
- High Blood Pressure: 6 people, 13.64%
* Approximation only. Some reports may have incomplete information.
Do you take Hydroxyurea and Vancomycin?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Hydroxyurea (17,240 reports)
- Vancomycin (17,165 reports)
Browse all drug interactions of Hydroxyurea and Vancomycin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Hydroxyurea:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Vancomycin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Hydroxyurea and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Vancomycin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on hydroxyurea and vancomycin (the active ingredients of Hydroxyurea and Vancomycin, respectively), and Hydroxyurea and Vancomycin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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