Hydroxyzine hydrochloride and Vascepa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hydroxyzine hydrochloride (hydroxyzine hydrochloride) and Vascepa (icosapent ethyl). Common drug interactions include headache among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Hydroxyzine hydrochloride and Vascepa. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Hydroxyzine hydrochloride?

Hydroxyzine hydrochloride has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 10,486 Hydroxyzine hydrochloride users. Check the latest studies of Hydroxyzine hydrochloride.

What is Vascepa?

Vascepa has active ingredients of icosapent ethyl. It is often used in high blood cholesterol. eHealthMe is studying from 5,894 Vascepa users. Check the latest studies of Vascepa.



On Aug, 02, 2026

12 people who take Hydroxyzine hydrochloride and Vascepa together, and have interactions are studied.

Hydroxyzine hydrochloride and Vascepa drug interactions.

What are the common drug interactions of Hydroxyzine Hydrochloride and Vascepa, by gender? *:

female:

  1. Headache (pain in head)
  2. Pain
  3. Abdominal discomfort
  4. Blood glucose increased
  5. Blood pressure increased
  6. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
  7. Fall
  8. Gastrointestinal infection (infection of stomach and intestine)
  9. Muscular weakness (muscle weakness)
  10. Nausea (feeling of having an urge to vomit)

male:

  1. Chronic kidney disease
  2. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  3. Sleep disorder
  4. Thrombosis (formation of a blood clot inside a blood vessel)
  5. Tremor (trembling or shaking movements in one or more parts of your body)
  6. Wound
  7. Blood potassium increased
  8. Dysstasia (difficulty in standing)
  9. Foot amputation (loss of foot)
  10. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

What are the common drug interactions of Hydroxyzine Hydrochloride and Vascepa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Blood sodium decreased
  2. Chest pain
  3. Dyspnoea (difficult or laboured respiration)
  4. Injection site erythema (redness at injection site)
  5. Injection site mass
  6. Injection site pain
  7. Low density lipoprotein
  8. Surgery

40-49:

  1. Blood potassium increased
  2. Chronic kidney disease
  3. Dysstasia (difficulty in standing)
  4. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  5. Tremor (trembling or shaking movements in one or more parts of your body)

50-59:

  1. Abdominal discomfort
  2. Blood pressure increased
  3. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
  4. Fall
  5. Gastrointestinal infection (infection of stomach and intestine)
  6. Headache (pain in head)
  7. Pain
  8. Patella fracture
  9. Sinusitis (inflammation of sinus)
  10. Urinary tract infection

60+:

  1. Blood glucose increased
  2. Headache (pain in head)
  3. Ill-defined disorder
  4. Neutropenia (an abnormally low number of neutrophils)
  5. Pain
  6. Muscular weakness (muscle weakness)
  7. Nausea (feeling of having an urge to vomit)
  8. Abdominal pain
  9. Asthenia (weakness)
  10. Death

What are the existing conditions these people have? *

  1. High Blood Pressure: 3 people, 25.00%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 25.00%
  3. Pain: 3 people, 25.00%
  4. Multiple Allergies (allergy to multiple agents): 2 people, 16.67%
  5. Urinary Tract Infection: 2 people, 16.67%
  6. Immunodeficiency Common Variable: 2 people, 16.67%
  7. Cough: 2 people, 16.67%
  8. Lung Neoplasm Malignant (cancer tumour of lung): 2 people, 16.67%
  9. Wheezing (a high-pitched whistling sound made while you breath): 1 person, 8.33%
  10. Haemorrhoids (a swollen vein or group of veins in the region of the anus): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Hydroxyzine hydrochloride and Vascepa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Hydroxyzine hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Vascepa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hydroxyzine hydrochloride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vascepa and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on hydroxyzine hydrochloride and icosapent ethyl (the active ingredients of Hydroxyzine hydrochloride and Vascepa, respectively), and Hydroxyzine hydrochloride and Vascepa (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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