Epival and Neck pain - a phase IV clinical study of FDA data

Summary:

Neck pain is reported as a side effect among people who take Epival (divalproex sodium), especially for people who are male, 30-39 old, also take Robaxin, and have Osteoporosis.

The phase IV clinical study analyzes which people have Neck pain when taking Epival. It is created by eHealthMe based on reports of 968 people who have side effects when taking Epival from the FDA, and is updated regularly.

What is Epival?

Epival has active ingredients of divalproex sodium. It is often used in epilepsy. eHealthMe is studying from 1,088 Epival users. Check the latest studies of Epival.

What is Neck pain?

Neck pain is found to be associated with 2,075 drugs and 2,821 conditions by eHealthMe. Check the latest studies of Neck pain.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 02, 2026

968 people reported to have side effects when taking Epival.
Among them, 11 people (1.14%) have Neck pain.

Could Epival cause Neck pain?

Among these 11 people:

What is the gender of people who have Neck pain when taking Epival? *

  • female: 45.45 %
  • male: 54.55 %

What is the age of people who have Neck pain when taking Epival? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 28.57 %
  • 30-39: 57.14 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 14.29 %

What are other drugs people take besides Epival? *

  1. Clonazepam: 3 people, 27.27%
  2. Robaxin: 3 people, 27.27%
  3. Zolpidem: 2 people, 18.18%
  4. Meloxicam: 2 people, 18.18%
  5. Effexor: 2 people, 18.18%
  6. Indomethacin: 2 people, 18.18%
  7. Luvox: 2 people, 18.18%
  8. Ibuprofen: 2 people, 18.18%
  9. Neurontin: 2 people, 18.18%
  10. Olanzapine: 2 people, 18.18%

What are other side effects people have besides Neck pain? *

  1. Back Pain: 7 people, 63.64%
  2. Fatigue (feeling of tiredness): 3 people, 27.27%
  3. Ankylosing Spondylitis (type of arthritis affecting the spine): 3 people, 27.27%
  4. Muscle Spasms (muscle contraction): 3 people, 27.27%
  5. Joint Pain: 3 people, 27.27%
  6. Discomfort: 3 people, 27.27%
  7. Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 3 people, 27.27%
  8. Feeling Drunk: 2 people, 18.18%
  9. Hypoaesthesia (reduced sense of touch or sensation): 2 people, 18.18%
  10. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 18.18%

What are the existing conditions these people have? *

  1. Osteoporosis (bones weak and more likely to break): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Epival and have Neck pain?

- Check whether Neck pain is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Epival:

Neck pain treatments and more:

How severe was Neck pain and when was it recovered:

Expand to all the drugs that have ingredients of divalproex sodium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Epival:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Neck pain:

Browse all the conditions that are associated with Neck pain:


How the study uses the data?

The study uses data from the FDA. It is based on divalproex sodium (the active ingredients of Epival) and Epival (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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