Hydroxyzine and Alendronic acid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hydroxyzine (hydroxyzine hydrochloride) and Alendronic acid (alendronate sodium). Common drug interactions include abdominal pain upper among females and swelling among males.

The phase IV clinical study analyzes what interactions people have when they take Hydroxyzine and Alendronic acid. It is created by eHealthMe based on reports of 71 people who take the same drugs from the FDA, and is updated regularly.

What is Hydroxyzine?

Hydroxyzine has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 54,070 Hydroxyzine users. Check the latest studies of Hydroxyzine.

What is Alendronic acid?

Alendronic acid has active ingredients of alendronate sodium. It is often used in osteoporosis. eHealthMe is studying from 18,408 Alendronic acid users. Check the latest studies of Alendronic acid.

On Aug, 12, 2026

71 people who take Hydroxyzine and Alendronic acid together, and have interactions are studied.

Hydroxyzine and Alendronic acid drug interactions.

What are the common drug interactions of Hydroxyzine and Alendronic Acid, by gender? *:

female:

Abdominal pain upper
Vomiting
Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents)
Renal failure (kidney dysfunction)
Dizziness
Fall
Hypotension (abnormally low blood pressure)
Respiratory failure (inadequate gas exchange by the respiratory system)
Chest pain
Drug level increased

male:

Swelling
Abnormal loss of weight
Thirst
Dizziness
Dry skin
Fatigue (feeling of tiredness)
Lip swelling
Palpitations (feelings or sensations that your heart is pounding or racing)
Prostate cancer metastatic
Rash erythematous (redness of the skin)

What are the common drug interactions of Hydroxyzine and Alendronic Acid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Oral candidiasis (fungal infection of mouth)
Oral hairy leukoplakia (a white patch on the side of the tongue)
Pneumonia

40-49:

n/a

50-59:

Abdominal pain upper
Vomiting
Nausea (feeling of having an urge to vomit)

60+:

Dizziness
Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents)
Haemodynamic instability (disturbances in the blood movement in our body)
Headache (pain in head)
Rash macular (small, flat red spots)
Swelling
Tremor (trembling or shaking movements in one or more parts of your body)
Lip swelling
Abdominal discomfort
Anxiety disorder

What are the existing conditions these people have? *

High Blood Pressure: 8 people, 11.27%
Depression: 6 people, 8.45%
Malaise (a feeling of general discomfort or uneasiness): 5 people, 7.04%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 4 people, 5.63%
Psoriasis (immune-mediated disease that affects the skin): 4 people, 5.63%

* Approximation only. Some reports may have incomplete information.

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