Hydroxyzine and Levemir drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Hydroxyzine (hydroxyzine hydrochloride) and Levemir (insulin detemir recombinant). Common drug interactions include heart rate decreased among females and dizziness among males.
The phase IV clinical study analyzes what interactions people have when they take Hydroxyzine and Levemir. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.
What is Hydroxyzine?
Hydroxyzine has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 54,069 Hydroxyzine users. Check the latest studies of Hydroxyzine.
What is Levemir?
Levemir has active ingredients of insulin detemir recombinant. It is often used in diabetes. eHealthMe is studying from 13,850 Levemir users. Check the latest studies of Levemir.
37 people who take Hydroxyzine and Levemir together, and have interactions are studied.

What are the common drug interactions of Hydroxyzine and Levemir, by gender? *:
female:
- Heart rate decreased
- Hyperglycaemia (high blood sugar)
- Hypertension (high blood pressure)
- Ileus (a painful obstruction of the ileum or other part of the intestine)
- Injection site pain
- Injection site urticaria (rash of round, red welts on the skin at injection site)
- Loss of consciousness
- Nausea (feeling of having an urge to vomit)
- Pancreatitis (inflammation of pancreas)
- Paronychia (infection in the tissues adjacent to a nail on a finger or toe)
male:
- Dizziness
- Constipation
- Diastolic dysfunction
- Diverticulum intestinal (a pouch that is attached to the first part of the small intestine)
- Drug diversion
- Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
- Dysaesthesia (abnormal sensation)
- Dysarthria (speech disorder)
- Dysphagia (a condition in which swallowing is difficult or painful)
- Dysphonia (speech disorder attributable to a disorder of phonation)
What are the common drug interactions of Hydroxyzine and Levemir, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Dyspnoea (difficult or laboured respiration)
- Respiratory distress (difficulty in breathing)
- Tachypnoea (a condition of rapid breathing over 20 per minute)
40-49:
- Blood glucose increased
- Cholecystitis chronic (long lasting infection of gallbladder)
- Cough
- Death
- Gallbladder injury
- Injection site urticaria (rash of round, red welts on the skin at injection site)
- Paronychia (infection in the tissues adjacent to a nail on a finger or toe)
- Respiratory tract infection
- Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
- Urticaria (rash of round, red welts on the skin that itch intensely)
50-59:
- Oedema peripheral (superficial swelling)
- Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
- Blood glucose increased
- Breast cancer
- Diabetes mellitus inadequate control
- Erythrodermic psoriasis (generalized redness of the skin)
- Hypertension (high blood pressure)
- Infection
- Injection site pain
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
60+:
- Blood glucose increased
- Constipation
- Balance disorder
- Cellulitis (infection under the skin)
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Diastolic dysfunction
- Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
- Diverticulum intestinal (a pouch that is attached to the first part of the small intestine)
- Drug diversion
- Drug ineffective
What are the existing conditions these people have? *
- High Blood Pressure: 8 people, 21.62%
- Itching: 5 people, 13.51%
- High Blood Cholesterol: 4 people, 10.81%
- Weight Loss: 3 people, 8.11%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 8.11%
- Pain: 3 people, 8.11%
- Nausea (feeling of having an urge to vomit): 3 people, 8.11%
- Type 2 Diabetes: 3 people, 8.11%
- Hepatitis C: 2 people, 5.41%
- Cardiac Disorder: 2 people, 5.41%
* Approximation only. Some reports may have incomplete information.
Do you take Hydroxyzine and Levemir?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Hydroxyzine (54,069 reports)
- Levemir (13,850 reports)
Browse all drug interactions of Hydroxyzine and Levemir:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Hydroxyzine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Levemir:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Hydroxyzine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Levemir and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Ate? ?, Arikan MF, Kaplan M, Altay M, "Hydroxyzine induced pancytopenia and petechial rashes: a rare complication", Journal Of Contemporary Medicine, 2017 Jan .
- Ate? ?, Arikan MF, Kaplan M, Altay M, "Hydroxyzine induced pancytopenia and petechial rashes: a rare complication", Journal Of Contemporary Medicine, 2017 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on hydroxyzine hydrochloride and insulin detemir recombinant (the active ingredients of Hydroxyzine and Levemir, respectively), and Hydroxyzine and Levemir (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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