Hydroxyzine and Matulane drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Hydroxyzine (hydroxyzine hydrochloride) and Matulane (procarbazine hydrochloride). Common drug interactions include blood glucose increased among females and nausea among males.
The phase IV clinical study analyzes what interactions people have when they take Hydroxyzine and Matulane. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.
What is Hydroxyzine?
Hydroxyzine has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 54,069 Hydroxyzine users. Check the latest studies of Hydroxyzine.
What is Matulane?
Matulane has active ingredients of procarbazine hydrochloride. eHealthMe is studying from 3,440 Matulane users. Check the latest studies of Matulane.
15 people who take Hydroxyzine and Matulane together, and have interactions are studied.

What are the common drug interactions of Hydroxyzine and Matulane, by gender? *:
female:
- Blood glucose increased
- Dehydration (dryness resulting from the removal of water)
- Dizziness
- Fatigue (feeling of tiredness)
- Iron deficiency anaemia
- Melaena (the passage of black, tarry stools)
- Myalgia (muscle pain)
- Neutropenia (an abnormally low number of neutrophils)
- Thrombocytopenia (decrease of platelets in blood)
- Urinary tract infection
male:
- Nausea (feeling of having an urge to vomit)
- Fatigue (feeling of tiredness)
- Haemoglobin decreased
- Leukopenia (less number of white blood cells in blood)
- Malignant neoplasm progression (cancer tumour came back)
- Neutropenia (an abnormally low number of neutrophils)
- Vomiting
What are the common drug interactions of Hydroxyzine and Matulane, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Haemoglobin decreased
- Leukopenia (less number of white blood cells in blood)
- Neutropenia (an abnormally low number of neutrophils)
30-39:
- Iron deficiency anaemia
- Melaena (the passage of black, tarry stools)
- Myalgia (muscle pain)
- Nausea (feeling of having an urge to vomit)
- Seizure (abnormal excessive or synchronous neuronal activity in the brain)
- Asthenia (weakness)
40-49:
- Nausea (feeling of having an urge to vomit)
50-59:
- Dizziness
- Nausea (feeling of having an urge to vomit)
- Neutropenia (an abnormally low number of neutrophils)
- Thrombocytopenia (decrease of platelets in blood)
60+:
- Blood glucose increased
- Dehydration (dryness resulting from the removal of water)
- Urinary tract infection
What are the existing conditions these people have? *
- Brain Neoplasm Malignant (brain cancer tumour): 12 people, 80.00%
- Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 1 person, 6.67%
- Hodgkin's Lymphoma (cancer originating from white blood cells): 1 person, 6.67%
- Brain Neoplasm (tumour of brain): 1 person, 6.67%
* Approximation only. Some reports may have incomplete information.
Do you take Hydroxyzine and Matulane?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Hydroxyzine (54,069 reports)
- Matulane (3,440 reports)
Browse all drug interactions of Hydroxyzine and Matulane:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Hydroxyzine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Matulane:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Hydroxyzine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Matulane and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Ate? ?, Arikan MF, Kaplan M, Altay M, "Hydroxyzine induced pancytopenia and petechial rashes: a rare complication", Journal Of Contemporary Medicine, 2017 Jan .
- Ate? ?, Arikan MF, Kaplan M, Altay M, "Hydroxyzine induced pancytopenia and petechial rashes: a rare complication", Journal Of Contemporary Medicine, 2017 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on hydroxyzine hydrochloride and procarbazine hydrochloride (the active ingredients of Hydroxyzine and Matulane, respectively), and Hydroxyzine and Matulane (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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