Hydroxyzine and Methotrexate sodium drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Hydroxyzine (hydroxyzine hydrochloride) and Methotrexate sodium (methotrexate sodium). Common drug interactions include bone pain among females and pyrexia among males.
The phase IV clinical study analyzes what interactions people have when they take Hydroxyzine and Methotrexate sodium. It is created by eHealthMe based on reports of 151 people who take the same drugs from the FDA, and is updated regularly.
What is Hydroxyzine?
Hydroxyzine has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 54,069 Hydroxyzine users. Check the latest studies of Hydroxyzine.
What is Methotrexate sodium?
Methotrexate sodium has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. eHealthMe is studying from 97,679 Methotrexate sodium users. Check the latest studies of Methotrexate sodium.
151 people who take Hydroxyzine and Methotrexate sodium together, and have interactions are studied.

What are the common drug interactions of Hydroxyzine and Methotrexate sodium, by gender? *
What are the common drug interactions of Hydroxyzine and Methotrexate sodium, by age (0-1 to 60+)? *
What are the existing conditions these people have? *
* Approximation only. Some reports may have incomplete information.
Do you take Hydroxyzine and Methotrexate sodium?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Hydroxyzine (54,069 reports)
- Methotrexate sodium (97,679 reports)
Browse all drug interactions of Hydroxyzine and Methotrexate sodium:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Hydroxyzine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Methotrexate sodium:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Hydroxyzine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Methotrexate sodium and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Henien M, Carey B, Hullah E, Sproat C, Patel V, "methotrexate-associated osteonecrosis of the jaw: A report of two cases", Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 2017 Dec .
- Ate? ?, Arikan MF, Kaplan M, Altay M, "Hydroxyzine induced pancytopenia and petechial rashes: a rare complication", Journal Of Contemporary Medicine, 2017 Jan .
- Henien M, Carey B, Hullah E, Sproat C, Patel V, "methotrexate-associated osteonecrosis of the jaw: A report of two cases", Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 2017 Dec .
- Ate? ?, Arikan MF, Kaplan M, Altay M, "Hydroxyzine induced pancytopenia and petechial rashes: a rare complication", Journal Of Contemporary Medicine, 2017 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on hydroxyzine hydrochloride and methotrexate sodium (the active ingredients of Hydroxyzine and Methotrexate sodium, respectively), and Hydroxyzine and Methotrexate sodium (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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