Hydroxyzine and Oxervate drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Hydroxyzine (hydroxyzine hydrochloride) and Oxervate (cenegermin-bkbj). Common drug interactions include eye pain among females and eye pain among males.
The phase IV clinical study analyzes what interactions people have when they take Hydroxyzine and Oxervate. It is created by eHealthMe based on reports of 73 people who take the same drugs from the FDA, and is updated regularly.
What is Hydroxyzine?
Hydroxyzine has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 54,069 Hydroxyzine users. Check the latest studies of Hydroxyzine.
What is Oxervate?
Oxervate has active ingredients of cenegermin-bkbj. eHealthMe is studying from 7,219 Oxervate users. Check the latest studies of Oxervate.
73 people who take Hydroxyzine and Oxervate together, and have interactions are studied.

What are the common drug interactions of Hydroxyzine and Oxervate, by gender? *:
female:
- Eye pain
- Eye irritation
- Menstruation irregular
- Vision blurred
- Photophobia (extreme sensitivity to light)
- Dry eye (lack of adequate tears)
- Eyelid pain
- Hospitalisation
- Ocular hyperaemia (an abnormally large amount of blood in eye)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
male:
- Eye pain
- Hospitalisation
- Fall
- Fatigue (feeling of tiredness)
- Heart rate increased
- Hypotension (abnormally low blood pressure)
- Lip swelling
- Malaise (a feeling of general discomfort or uneasiness)
- Ocular hyperaemia (an abnormally large amount of blood in eye)
- Sinus disorder (disease of sinus)
What are the common drug interactions of Hydroxyzine and Oxervate, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Eyelid pain
40-49:
- Eye pain
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Hypersensitivity
- Menstruation irregular
- Pulmonary embolism (blockage of the main artery of the lung)
- Death
- Eye irritation
- Vision blurred
50-59:
- Death
- Eye pain
- Hospitalisation
- Malaise (a feeling of general discomfort or uneasiness)
60+:
- Eye pain
- Eye irritation
- Disease progression
- Erythema of eyelid (redness of the eyelid)
- Eye discharge
- Eye infection fungal
- Eye inflammation
- Eyelid pain
- Fall
- Fatigue (feeling of tiredness)
What are the existing conditions these people have? *
- Neurotrophic Keratopathy (decreased corneal sensitivity and poor corneal healing): 58 people, 79.45%
- Ulcerative Keratitis (ulcerative inflammation of the cornea): 10 people, 13.70%
- Hypoaesthesia Eye (reduced sense of touch or sensation on eyes): 10 people, 13.70%
* Approximation only. Some reports may have incomplete information.
Do you take Hydroxyzine and Oxervate?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Hydroxyzine (54,069 reports)
- Oxervate (7,219 reports)
Browse all drug interactions of Hydroxyzine and Oxervate:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Hydroxyzine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Oxervate:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Hydroxyzine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Oxervate and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Ate? ?, Arikan MF, Kaplan M, Altay M, "Hydroxyzine induced pancytopenia and petechial rashes: a rare complication", Journal Of Contemporary Medicine, 2017 Jan .
- Ate? ?, Arikan MF, Kaplan M, Altay M, "Hydroxyzine induced pancytopenia and petechial rashes: a rare complication", Journal Of Contemporary Medicine, 2017 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on hydroxyzine hydrochloride and cenegermin-bkbj (the active ingredients of Hydroxyzine and Oxervate, respectively), and Hydroxyzine and Oxervate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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