Lotronex and Diovan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lotronex (alosetron hydrochloride) and Diovan (valsartan). Common drug interactions include pneumonia among females and abdominal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Lotronex and Diovan. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.

What is Lotronex?

Lotronex has active ingredients of alosetron hydrochloride. It is often used in irritable bowel syndrome. eHealthMe is studying from 6,841 Lotronex users. Check the latest studies of Lotronex.

What is Diovan?

Diovan has active ingredients of valsartan. It is often used in high blood pressure. eHealthMe is studying from 83,153 Diovan users. Check the latest studies of Diovan.

On Jul, 14, 2026

31 people who take Lotronex and Diovan together, and have interactions are studied.

What are the common drug interactions of Lotronex and Diovan, by gender? *:

female:

Pneumonia
Post procedural infection
Pyelonephritis (inflammation of kidney caused by bacteria)
Renal failure (kidney dysfunction)
Road traffic accident
Sepsis (a severe blood infection that can lead to organ failure and death)
Sleep disorder
Small bowel angioedema (small bowel rapid swelling)
Snoring
Abdominal pain

male:

Abdominal pain
Diarrhoea
Dyspepsia (indigestion)
Emotional distress
Faecal incontinence (a lack of control over passing stool)
Malabsorption (a state arising from abnormality in absorption of food nutrients across the gastrointestinal (gi) tract)
Nausea (feeling of having an urge to vomit)
Renal failure (kidney dysfunction)
Abdominal distension
Abdominal pain lower

What are the common drug interactions of Lotronex and Diovan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal pain
Constipation
Diarrhoea

30-39:

Vomiting
Constipation
Abdominal distension
Abdominal injury
Abdominal pain
Adverse event
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Blood in stool
Colitis (inflammation of colon)
Contusion (a type of hematoma of tissue in which capillaries)

40-49:

Abdominal distension
Abdominal pain
Abdominal pain lower
Blood in stool
Constipation
Dyspepsia (indigestion)
Muscle cramp (painful sensation caused by muscle contraction)
Nausea (feeling of having an urge to vomit)

50-59:

Fatigue (feeling of tiredness)
Sedation
Alopecia (absence of hair from areas of the body)
Anaemia (lack of blood)
Asthma
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Constipation
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Hepatic enzyme increased
Hepatic steatosis (fatty liver disease)

60+:

Abdominal pain
Abdominal pain upper
Dyspnoea exertional (breathlessness or shortness of breath)
Rectal haemorrhage (bleeding from anus)
Aortic valve sclerosis (narrowing of the aortic valve)
Diarrhoea
Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
Mitral valve incompetence (inefficient heart valve)
Pulmonary valve incompetence
Syncope (loss of consciousness with an inability to maintain postural tone)

What are the existing conditions these people have? *

Diarrhea: 5 people, 16.13%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 6.45%

* Approximation only. Some reports may have incomplete information.

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