Losartan and Piperacillin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Losartan (losartan potassium) and Piperacillin (piperacillin sodium). Common drug interactions include blood creatine phosphokinase increased among females and pulmonary embolism among males.
The phase IV clinical study analyzes what interactions people have when they take Losartan and Piperacillin. It is created by eHealthMe based on reports of 81 people who take the same drugs from the FDA, and is updated regularly.
What is Losartan?
Losartan has active ingredients of losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 177,686 Losartan users. Check the latest studies of Losartan.
What is Piperacillin?
Piperacillin has active ingredients of piperacillin sodium. eHealthMe is studying from 5,597 Piperacillin users. Check the latest studies of Piperacillin.
81 people who take Losartan and Piperacillin together, and have interactions are studied.

What are the common drug interactions of Losartan and Piperacillin, by gender? *:
female:
- Blood creatine phosphokinase increased
- Cellulitis (infection under the skin)
- Cough
- Cytomegalovirus test positive
- Decreased appetite
- Depressed level of consciousness
- Epigastric discomfort
- Gastroenteritis (inflammation of stomach and intestine)
- Gingivitis (inflammation of gums)
- Hyperlipidaemia (presence of excess lipids in the blood)
male:
- Pulmonary embolism (blockage of the main artery of the lung)
- Renal failure (kidney dysfunction)
- Pneumonia
- Abdominal distension
- Alanine aminotransferase increased
- Anaemia (lack of blood)
- Bk virus infection
- Blood albumin decreased
- Blood triglycerides increased
- Blood urea increased
What are the common drug interactions of Losartan and Piperacillin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Blood creatine phosphokinase increased
- Gastroenteritis (inflammation of stomach and intestine)
- Hyperlipidaemia (presence of excess lipids in the blood)
- Hyperuricaemia (level of uric acid in the blood that is abnormally high)
- Iron deficiency anaemia
- Menorrhagia (an abnormally heavy bleeding and prolonged menstrual period at regular intervals)
- Nasopharyngitis (inflammation of the nasopharynx)
- Osteonecrosis (death of bone)
- Otitis externa (external ear infection)
- Purpura (purplish discoloration of the skin)
30-39:
- Abdominal distension
- Alanine aminotransferase increased
- Anaemia (lack of blood)
- Bk virus infection
- Blood albumin decreased
- Blood triglycerides increased
- Blood urea increased
- Blood uric acid increased
- Decreased appetite
- Diarrhoea
40-49:
n/a
50-59:
- Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
- Cellulitis (infection under the skin)
- Dyspepsia (indigestion)
- Nephrogenic anaemia (anaemia due to kidney disease)
- Oxygen saturation decreased
- Perioral dermatitis (facial rash that causes bumps to develop around the mouth)
- Psoriasis (immune-mediated disease that affects the skin)
- Renal failure acute (rapid kidney dysfunction)
- Sacroiliitis (an inflammation of the sacroiliac joint)
- Secondary hyperthyroidism
60+:
- Abdominal pain
- Constipation
- Renal failure (kidney dysfunction)
- Febrile neutropenia (fever with reduced white blood cells)
- Abscess (pus)
- Acanthosis (thickening of the skin)
- Aspartate aminotransferase increased
- Cardiac arrest
- Cellulitis (infection under the skin)
- Chronic kidney disease
What are the existing conditions these people have? *
- Pain: 12 people, 14.81%
- Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 12 people, 14.81%
- Burkitt Lymphoma (cancer of the lymphatic system): 8 people, 9.88%
- Constipation: 7 people, 8.64%
- Mucosal Inflammation (infection of mucous membrane): 7 people, 8.64%
- Diffuse Large B-Cell Lymphoma Stage Iv (cancer of b cells, a type of white blood cell-stage iv): 7 people, 8.64%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 8.64%
- Transitional Cell Carcinoma (cancer tumour inner most layer of urinary system): 7 people, 8.64%
- Headache (pain in head): 5 people, 6.17%
- Diarrhea: 5 people, 6.17%
* Approximation only. Some reports may have incomplete information.
Do you take Losartan and Piperacillin?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Losartan (177,686 reports)
- Piperacillin (5,597 reports)
Browse all drug interactions of Losartan and Piperacillin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Losartan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Piperacillin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Losartan and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Piperacillin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Lai SW, Lin HF, Lin CL, Liao KF, "No association between losartan use and acute pancreatitis in hypertensive patients", Eur J Hosp Pharm, 2017 Mar .
- Lai SW, Lin HF, Lin CL, Liao KF, "No association between losartan use and acute pancreatitis in hypertensive patients", Eur J Hosp Pharm, 2017 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on losartan potassium and piperacillin sodium (the active ingredients of Losartan and Piperacillin, respectively), and Losartan and Piperacillin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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