Hydroxyzine and Tobramycin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hydroxyzine (hydroxyzine hydrochloride) and Tobramycin (tobramycin). Common drug interactions include dizziness among females and mucosal inflammation among males.

The phase IV clinical study analyzes what interactions people have when they take Hydroxyzine and Tobramycin. It is created by eHealthMe based on reports of 57 people who take the same drugs from the FDA, and is updated regularly.

What is Hydroxyzine?

Hydroxyzine has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 54,069 Hydroxyzine users. Check the latest studies of Hydroxyzine.

What is Tobramycin?

Tobramycin has active ingredients of tobramycin. It is often used in cystic fibrosis. eHealthMe is studying from 3,579 Tobramycin users. Check the latest studies of Tobramycin.

On Jul, 26, 2026

57 people who take Hydroxyzine and Tobramycin together, and have interactions are studied.

Hydroxyzine and Tobramycin drug interactions.

What are the common drug interactions of Hydroxyzine and Tobramycin, by gender? *:

female:

Dizziness
Drug ineffective
Dyspnoea (difficult or laboured respiration)
Epstein-barr virus infection
Fall
Frequent bowel movements
Gallbladder operation
Hepatitis acute
Hepatotoxicity (chemical-driven liver damage)
Influenza

male:

Mucosal inflammation (infection of mucous membrane)
Abnormal behaviour
Enuresis (repeated inability to control urination)
Fall
Fluid retention (an abnormal accumulation of fluid in the blood)
Haematemesis (vomiting of blood)
Hepatitis c
Ileus (a painful obstruction of the ileum or other part of the intestine)
Pain
Rectal haemorrhage (bleeding from anus)

What are the common drug interactions of Hydroxyzine and Tobramycin, by age (0-1 to 60+)? *:

0-1:

Ileus (a painful obstruction of the ileum or other part of the intestine)
Mucosal inflammation (infection of mucous membrane)
Pain
Rectal haemorrhage (bleeding from anus)
Venoocclusive liver disease (small veins in the liver are obstructed)
Hepatotoxicity (chemical-driven liver damage)
Liver injury

2-9:

Mucosal inflammation (infection of mucous membrane)
Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
Radiation mucositis (inflammation of oral mucosa resulting from chemotherapeutic agents or ionizing radiation)
Heart transplant
Pulmonary hypertension (increase in blood pressure in the lung artery)
Restrictive cardiomyopathy (a condition in which the walls of the lower chambers of the heart (the ventricles) are abnormally rigid and lack the flexibility)

10-19:

Abdominal discomfort
Frequent bowel movements
Renal failure acute (rapid kidney dysfunction)

20-29:

Cell death
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Hepatitis acute
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)

30-39:

Gallbladder operation
Respiratory disorder (respiratory disease)

40-49:

Osteoporosis (bones weak and more likely to break)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Asthenia (weakness)
Bone density decreased
Emotional distress
Fatigue (feeling of tiredness)
Osteopenia (a condition where bone mineral density is lower than normal)
Pain
Renal impairment (severely reduced kidney function)
Chronic kidney disease

50-59:

Chronic kidney disease
Autonomic neuropathy (malfunction of the autonomic nervous system (ans))
Bone density decreased
Cardiomegaly (increased size of heart than normal)
Dementia (madness)
Dry eye (lack of adequate tears)
Fall
Haemorrhage (bleeding)
Infection
Migraine with aura (headache with vision weakness)

60+:

Cataract (clouding of the lens inside the eye)
Infusion related reaction
Back pain
Dysphonia (speech disorder attributable to a disorder of phonation)
Dyspnoea (difficult or laboured respiration)
Fall
Infection
Pulmonary mass
Spinal fracture (fracture in one of vertebrae)
Infusion site haemorrhage (bleeding from infusion site)

What are the existing conditions these people have? *

Bone Marrow Conditioning Regimen: 8 people, 14.04%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 12.28%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 7 people, 12.28%
Pain: 6 people, 10.53%
Immunodeficiency Common Variable: 5 people, 8.77%
Hiv Infection: 5 people, 8.77%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 7.02%
Wheezing (a high-pitched whistling sound made while you breath): 3 people, 5.26%
Eosinophilia (eosinophil count in the peripheral blood exceeds): 3 people, 5.26%
Dyspnea (difficult or laboured breathing): 3 people, 5.26%

* Approximation only. Some reports may have incomplete information.

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