1. Home
  2. Analysis
  3. Narcan
  4. Ibrance

Narcan and Ibrance drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Narcan (naloxone hydrochloride) and Ibrance (palbociclib). Common drug interactions include fatigue among females.

The phase IV clinical study analyzes what interactions people have when they take Narcan and Ibrance. It is created by eHealthMe based on reports of 53 people who take the same drugs from the FDA, and is updated regularly.

What is Narcan?

Narcan has active ingredients of naloxone hydrochloride. eHealthMe is studying from 3,687 Narcan users. Check the latest studies of Narcan.

What is Ibrance?

Ibrance has active ingredients of palbociclib. eHealthMe is studying from 104,433 Ibrance users. Check the latest studies of Ibrance.

On Jul, 19, 2025

53 people who take Narcan and Ibrance together, and have interactions are studied.

Narcan and Ibrance drug interactions.

What are the common drug interactions of Narcan and Ibrance, by gender? *:

female:

  1. Fatigue (feeling of tiredness)
  2. White blood cell count decreased
  3. Dyspnoea (difficult or laboured respiration)
  4. Hepatic enzyme increased
  5. Hypoaesthesia (reduced sense of touch or sensation)
  6. Nerve injury
  7. Red blood cell count decreased
  8. Sinusitis (inflammation of sinus)
  9. Burning sensation
  10. Pain in extremity

male:

n/a

What are the common drug interactions of Narcan and Ibrance, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Brain neoplasm (tumour of brain)
  2. Disease progression

40-49:

  1. Alopecia (absence of hair from areas of the body)
  2. Fatigue (feeling of tiredness)
  3. Nausea (feeling of having an urge to vomit)
  4. White blood cell count decreased
  5. Headache (pain in head)
  6. Blood glucose decreased
  7. Decreased appetite
  8. Hospitalisation
  9. Neoplasm progression (growth of tumour)
  10. Pneumonia

50-59:

  1. Gait disturbance
  2. Herpes zoster
  3. Peroneal nerve palsy
  4. Sinusitis (inflammation of sinus)
  5. Arthralgia (joint pain)
  6. Heart rate decreased
  7. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
  8. Nausea (feeling of having an urge to vomit)
  9. Pain
  10. Decreased appetite

60+:

  1. Fatigue (feeling of tiredness)
  2. White blood cell count decreased
  3. Hypoaesthesia (reduced sense of touch or sensation)
  4. Nerve injury
  5. Neutropenia (an abnormally low number of neutrophils)
  6. Red blood cell count decreased
  7. Burning sensation
  8. Pain in extremity
  9. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  10. Infection

What are the existing conditions these people have? *

  1. Breast Cancer Female: 24 people, 45.28%
  2. Breast Cancer: 10 people, 18.87%

* Approximation only. Some reports may have incomplete information.

Do you take Narcan and Ibrance?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Narcan and Ibrance:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Narcan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ibrance:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Narcan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ibrance and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on naloxone hydrochloride and palbociclib (the active ingredients of Narcan and Ibrance, respectively), and Narcan and Ibrance (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe:

© 2025 eHealthMe.com. All rights reserved. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy.