Ibrance and Tacrolimus drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Ibrance (palbociclib) and Tacrolimus (tacrolimus). Common drug interactions include inner ear disorder among females.
The phase IV clinical study analyzes what interactions people have when they take Ibrance and Tacrolimus. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.
What is Ibrance?
Ibrance has active ingredients of palbociclib. eHealthMe is studying from 104,434 Ibrance users. Check the latest studies of Ibrance.
What is Tacrolimus?
Tacrolimus has active ingredients of tacrolimus. It is often used in kidney transplant. eHealthMe is studying from 116,160 Tacrolimus users. Check the latest studies of Tacrolimus.
18 people who take Ibrance and Tacrolimus together, and have interactions are studied.

What are the common drug interactions of Ibrance and Tacrolimus, by gender? *:
female:
- Inner ear disorder
- Vertigo
- Red blood cell count decreased
- White blood cell count decreased
- Alopecia (absence of hair from areas of the body)
- Death
- Decreased appetite
- Diarrhoea
- Dyspnoea (difficult or laboured respiration)
- Ejection fraction decreased (systolic heart failure)
male:
n/a
What are the common drug interactions of Ibrance and Tacrolimus, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Inner ear disorder
- Vertigo
- Asthenia (weakness)
- Decreased immune responsiveness
- Pain in jaw
- Tooth disorder (tooth disease)
- Tooth fracture
- Toothache (tooth pain)
- Immune system disorder
- Alopecia (absence of hair from areas of the body)
50-59:
- Abdominal pain upper
- Alopecia (absence of hair from areas of the body)
- Coronary arterial stent insertion
- Cystitis (inflammation of the wall of the bladder)
- Diarrhoea
- Fatigue (feeling of tiredness)
- Gastric neoplasm (a tumour that develops in the stomach)
- Urinary tract infection
60+:
- Fatigue (feeling of tiredness)
- Platelet count decreased
- Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
- Oral pain
- Pruritus (severe itching of the skin)
- Anion gap decreased
- Blood creatinine increased
- Blood urea increased
- Carbohydrate antigen 27.29 increased
- Diarrhoea
What are the existing conditions these people have? *
- Breast Cancer Female: 6 people, 33.33%
- Breast Cancer Metastatic: 3 people, 16.67%
- Breast Cancer: 3 people, 16.67%
- Stomatitis (inflammation of mucous membrane of mouth): 1 person, 5.56%
- Positron Emission Tomogram Abnormal: 1 person, 5.56%
- Nausea (feeling of having an urge to vomit): 1 person, 5.56%
- Metastases To Lung (cancer spreads to lung): 1 person, 5.56%
- Herpes Zoster: 1 person, 5.56%
- Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 1 person, 5.56%
- Cough: 1 person, 5.56%
* Approximation only. Some reports may have incomplete information.
Do you take Ibrance and Tacrolimus?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Ibrance (104,434 reports)
- Tacrolimus (116,160 reports)
Browse all drug interactions of Ibrance and Tacrolimus:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Ibrance:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Tacrolimus:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ibrance and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Tacrolimus and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on palbociclib and tacrolimus (the active ingredients of Ibrance and Tacrolimus, respectively), and Ibrance and Tacrolimus (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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