Ibrance and Vinorelbine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ibrance (palbociclib) and Vinorelbine (vinorelbine). Common drug interactions include malignant neoplasm progression among females.

The phase IV clinical study analyzes what interactions people have when they take Ibrance and Vinorelbine. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Ibrance?

Ibrance has active ingredients of palbociclib. eHealthMe is studying from 104,434 Ibrance users. Check the latest studies of Ibrance.

What is Vinorelbine?

Vinorelbine has active ingredients of vinorelbine. eHealthMe is studying from 6,381 Vinorelbine users. Check the latest studies of Vinorelbine.



On Jul, 08, 2026

17 people who take Ibrance and Vinorelbine together, and have interactions are studied.

Ibrance and Vinorelbine drug interactions.

What are the common drug interactions of Ibrance and Vinorelbine, by gender? *:

female:

  1. Malignant neoplasm progression (cancer tumour came back)
  2. Neutropenia (an abnormally low number of neutrophils)
  3. Decreased appetite
  4. Drug intolerance (drug sensitivity)
  5. Fractured sacrum
  6. General physical health deterioration (weak health status)
  7. Hepatic lesion
  8. Keratopathy (noninflammatory disease of the cornea)
  9. Lymphangiosis carcinomatosa (inflammation of the lymph vessels can lead to cancer)
  10. Palpitations (feelings or sensations that your heart is pounding or racing)

male:

n/a

What are the common drug interactions of Ibrance and Vinorelbine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Neoplasm progression (growth of tumour)

20-29:

  1. Malignant neoplasm progression (cancer tumour came back)
  2. Metastases to bone (cancer spreads to bone)
  3. Metastases to central nervous system (cancer spreads to central nervous system)
  4. Metastases to lymph nodes (cancer spreads to lymph node)
  5. Neutropenia (an abnormally low number of neutrophils)
  6. White blood cell count decreased

30-39:

n/a

40-49:

n/a

50-59:

  1. Asthenia (weakness)
  2. Breast cancer
  3. Breast cancer metastatic
  4. Drug intolerance (drug sensitivity)
  5. Fatigue (feeling of tiredness)
  6. Malignant neoplasm progression (cancer tumour came back)
  7. Neuropathy peripheral (surface nerve damage)
  8. Neutropenia (an abnormally low number of neutrophils)
  9. Pain
  10. Tumour marker increased

60+:

  1. Malignant neoplasm progression (cancer tumour came back)
  2. Abdominal pain upper
  3. Hepatic lesion
  4. Keratopathy (noninflammatory disease of the cornea)
  5. Lymphangiosis carcinomatosa (inflammation of the lymph vessels can lead to cancer)
  6. Metastases to bone (cancer spreads to bone)
  7. Metastases to liver (cancer spreads to liver)
  8. Neutropenia (an abnormally low number of neutrophils)
  9. Palpitations (feelings or sensations that your heart is pounding or racing)
  10. Pleural effusion (water on the lungs)

What are the existing conditions these people have? *

  1. Breast Cancer: 8 people, 47.06%
  2. Breast Cancer Metastatic: 4 people, 23.53%
  3. Pain: 2 people, 11.76%
  4. Neuropathy Peripheral (surface nerve damage): 2 people, 11.76%
  5. Rhabdomyosarcoma (cancer of the bone, soft tissues, or connective tissue (e.g., tendon or cartilage)): 1 person, 5.88%
  6. Breast Cancer Female: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ibrance and Vinorelbine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ibrance:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Vinorelbine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ibrance and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vinorelbine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on palbociclib and vinorelbine (the active ingredients of Ibrance and Vinorelbine, respectively), and Ibrance and Vinorelbine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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