Ibrutinib and Treanda drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Ibrutinib (ibrutinib) and Treanda (bendamustine hydrochloride). Common drug interactions include colitis ischaemic among females and respiratory failure among males.
The phase IV clinical study analyzes what interactions people have when they take Ibrutinib and Treanda. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.
What is Ibrutinib?
Ibrutinib has active ingredients of ibrutinib. eHealthMe is studying from 13,529 Ibrutinib users. Check the latest studies of Ibrutinib.
What is Treanda?
Treanda has active ingredients of bendamustine hydrochloride. It is often used in non-hodgkin's lymphoma. eHealthMe is studying from 4,411 Treanda users. Check the latest studies of Treanda.
23 people who take Ibrutinib and Treanda together, and have interactions are studied.

What are the common drug interactions of Ibrutinib and Treanda, by gender? *:
female:
- Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
- Anaemia (lack of blood)
- Cough
- Febrile neutropenia (fever with reduced white blood cells)
- Gastroenteritis clostridial (inflammation of stomach and intestine clostridial)
- Haemoglobin decreased
- Hypoaesthesia (reduced sense of touch or sensation)
- Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
- Nasal dryness (dry nose)
- Nasal ulcer (ulcer of nose)
male:
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Diarrhoea
- Drug intolerance (drug sensitivity)
- Hyperhidrosis (abnormally increased sweating)
- Impaired healing
- Septic shock (shock due to blood infection)
- Skin papilloma (a general medical term for a tumour of the skin or mucous membrane with finger-like projections)
- Splenomegaly (enlargement of spleen)
- Thrombocytopenia (decrease of platelets in blood)
- White blood cell count decreased
What are the common drug interactions of Ibrutinib and Treanda, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Anaemia (lack of blood)
- Febrile neutropenia (fever with reduced white blood cells)
- Gastroenteritis clostridial (inflammation of stomach and intestine clostridial)
- Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
- Pancreatitis (inflammation of pancreas)
- Thrombocytopenia (decrease of platelets in blood)
50-59:
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Hypotension (abnormally low blood pressure)
- Iridocyclitis (inflammation of the iris and ciliary body of the eye)
- Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
60+:
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Diarrhoea
- Drug intolerance (drug sensitivity)
- Hyperhidrosis (abnormally increased sweating)
- Impaired healing
- Septic shock (shock due to blood infection)
- Skin papilloma (a general medical term for a tumour of the skin or mucous membrane with finger-like projections)
- Splenomegaly (enlargement of spleen)
- Thrombocytopenia (decrease of platelets in blood)
- White blood cell count decreased
What are the existing conditions these people have? *
- Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 15 people, 65.22%
- Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 8 people, 34.78%
- Herpes Virus Infection: 2 people, 8.70%
- Diarrhea: 2 people, 8.70%
* Approximation only. Some reports may have incomplete information.
Do you take Ibrutinib and Treanda?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Ibrutinib and Treanda:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Ibrutinib:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Treanda:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ibrutinib and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Treanda and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on ibrutinib and bendamustine hydrochloride (the active ingredients of Ibrutinib and Treanda, respectively), and Ibrutinib and Treanda (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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