Ibu and Rayos drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ibu (ibuprofen) and Rayos (prednisone). Common drug interactions include drug ineffective among females and abnormal behaviour among males.

The phase IV clinical study analyzes what interactions people have when they take Ibu and Rayos. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Ibu?

Ibu has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 246,531 Ibu users. Check the latest studies of Ibu.

What is Rayos?

Rayos has active ingredients of prednisone. It is often used in systemic lupus erythematosus. eHealthMe is studying from 896 Rayos users. Check the latest studies of Rayos.

On Jul, 20, 2026

20 people who take Ibu and Rayos together, and have interactions are studied.

What are the common drug interactions of Ibu and Rayos, by gender? *:

female:

Drug ineffective
Idiopathic pulmonary fibrosis (chronic lung disease)
Pneumonia
Pruritus genital (uneasy irritation of the skin of the vagina and the surrounding area)
Malaise (a feeling of general discomfort or uneasiness)
Affective disorder (mental disorder)
Burning sensation
Cerebral haemorrhage (bleeding within the brain)
Diarrhoea
Drug effect decreased

male:

Abnormal behaviour
Anxiety
Autism spectrum disorder (developmental disabilities that can cause significant social, communication and behavioural challenges)
Blood pressure increased
Inflammation
Injection site pain
Injection site rash
Injection site swelling
Laceration (tearing of soft body tissue)

What are the common drug interactions of Ibu and Rayos, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Malaise (a feeling of general discomfort or uneasiness)

40-49:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Idiopathic pulmonary fibrosis (chronic lung disease)
Pneumonia
Pruritus genital (uneasy irritation of the skin of the vagina and the surrounding area)
Drug effect decreased
General physical health deterioration (weak health status)
Vomiting

50-59:

Drug ineffective
Hypercalcaemia (elevated calcium (ca+) level in the blood)
Obstructive airways disorder (a progressive disease that makes it hard to breathe)
Ovarian cancer stage iii
Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands)
Upper respiratory tract infection

60+:

Cerebral haemorrhage (bleeding within the brain)
Fatigue (feeling of tiredness)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Sudden death
Haematocrit decreased
Haemoglobin decreased
Injection site pain
Injection site rash
Injection site swelling
Laceration (tearing of soft body tissue)

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 13 people, 65.00%
Hyperlipidaemia (presence of excess lipids in the blood): 4 people, 20.00%
Muscle Aches (muscle pain): 4 people, 20.00%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 20.00%
Immunodeficiency Disorders: 4 people, 20.00%
Insomnia (sleeplessness): 4 people, 20.00%
Allergic Rhinitis: 4 people, 20.00%
Oedema (fluid collection in tissue): 4 people, 20.00%
Nausea (feeling of having an urge to vomit): 1 person, 5.00%
Dry Mouth: 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

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