Imbruvica and Innohep drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Imbruvica (ibrutinib) and Innohep (tinzaparin sodium). Common drug interactions include haemorrhage among males.

The phase IV clinical study analyzes what interactions people have when they take Imbruvica and Innohep. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Imbruvica?

Imbruvica has active ingredients of ibrutinib. It is often used in chronic lymphocytic leukemia (cll). eHealthMe is studying from 70,020 Imbruvica users. Check the latest studies of Imbruvica.

What is Innohep?

Innohep has active ingredients of tinzaparin sodium. eHealthMe is studying from 9,243 Innohep users. Check the latest studies of Innohep.

On Jul, 18, 2026

18 people who take Imbruvica and Innohep together, and have interactions are studied.

Imbruvica and Innohep drug interactions.

What are the common drug interactions of Imbruvica and Innohep, by gender? *:

female:

n/a

male:

Haemorrhage (bleeding)
Pulmonary embolism (blockage of the main artery of the lung)
Lower respiratory tract infection
Muscle spasms (muscle contraction)
Nausea (feeling of having an urge to vomit)
Respiratory tract infection
Tachyarrhythmia (disturbance of the heart rhythm in which the heart rate is abnormally increased)
Vertigo
Vomiting
Abdominal pain

What are the common drug interactions of Imbruvica and Innohep, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Catheter site haemorrhage (bleeding at catheter site)

60+:

Asthenia (weakness)
Atelectasis (partial or complete collapse of the lung)
Respiratory tract infection
Tachyarrhythmia (disturbance of the heart rhythm in which the heart rate is abnormally increased)
Vertigo
Vomiting
Abdominal pain
Arrhythmia (irregular heartbeat)
Death
Hallucination, visual (seeing things that aren't there)

What are the existing conditions these people have? *

Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 8 people, 44.44%
Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 7 people, 38.89%
Pulmonary Embolism (blockage of the main artery of the lung): 5 people, 27.78%
High Blood Pressure: 2 people, 11.11%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 2 people, 11.11%
Waldenstrom's Macroglobulinaemia (cancer affects small lymphocytes (white blood cells)): 1 person, 5.56%
Sedation: 1 person, 5.56%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 1 person, 5.56%
Hypoglycemia (low blood sugar): 1 person, 5.56%
Enlarged Prostate: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

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