Imbruvica and Methylphenidate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Imbruvica (ibrutinib) and Methylphenidate (methylphenidate). Common drug interactions include vomiting among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Imbruvica and Methylphenidate. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Imbruvica?

Imbruvica has active ingredients of ibrutinib. It is often used in chronic lymphocytic leukemia (cll). eHealthMe is studying from 70,020 Imbruvica users. Check the latest studies of Imbruvica.

What is Methylphenidate?

Methylphenidate has active ingredients of methylphenidate. eHealthMe is studying from 8,216 Methylphenidate users. Check the latest studies of Methylphenidate.

On Jul, 31, 2026

14 people who take Imbruvica and Methylphenidate together, and have interactions are studied.

Imbruvica and Methylphenidate drug interactions.

What are the common drug interactions of Imbruvica and Methylphenidate, by gender? *:

female:

Vomiting
Abdominal pain upper
Fall
Multiple fractures
Postoperative wound infection
Blood thyroid stimulating hormone increased
Brain neoplasm (tumour of brain)

male:

Death
Alanine aminotransferase increased
Eye disorder
Lymphadenopathy (disease or enlargement of lymph nodes)
Nausea (feeling of having an urge to vomit)
Pain in extremity
Sinusitis (inflammation of sinus)
Blood glucose decreased
Constipation
Dyspnoea (difficult or laboured respiration)

What are the common drug interactions of Imbruvica and Methylphenidate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Hair disorder
Lip swelling
Swollen tongue (swelling of tongue)

50-59:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blood triglycerides increased
Diarrhoea
Eye disorder
Lymphadenopathy (disease or enlargement of lymph nodes)
Nausea (feeling of having an urge to vomit)
Pain in extremity
Sinusitis (inflammation of sinus)

60+:

Death
Fall
Multiple fractures
Postoperative wound infection
Blood glucose decreased
Brain neoplasm (tumour of brain)
Constipation
Dyspnoea (difficult or laboured respiration)
Hypertension (high blood pressure)
Vomiting

What are the existing conditions these people have? *

Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 8 people, 57.14%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 2 people, 14.29%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 1 person, 7.14%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 7.14%
Hypersensitivity: 1 person, 7.14%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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