Imitrex and Digoxin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Imitrex (sumatriptan succinate) and Digoxin (digoxin). Common drug interactions include mobility decreased among females and chest pain among males.

The phase IV clinical study analyzes what interactions people have when they take Imitrex and Digoxin. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.

What is Imitrex?

Imitrex has active ingredients of sumatriptan succinate. It is often used in migraine. eHealthMe is studying from 17,149 Imitrex users. Check the latest studies of Imitrex.

What is Digoxin?

Digoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 93,740 Digoxin users. Check the latest studies of Digoxin.

On Aug, 01, 2026

44 people who take Imitrex and Digoxin together, and have interactions are studied.

What are the common drug interactions of Imitrex and Digoxin, by gender? *:

female:

Mobility decreased (ability to move is reduced)
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Pain in extremity
Dyspnoea (difficult or laboured respiration)
Depression
Multiple injuries
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Palpitations (feelings or sensations that your heart is pounding or racing)
Skin discolouration (change of skin colour)
Skin hypopigmentation (loss of skin colour)

male:

Chest pain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Rhinorrhoea (watery mucus discharge from the nose)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Vision blurred
Visual impairment
Anaemia (lack of blood)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Asthenia (weakness)
Back pain

What are the common drug interactions of Imitrex and Digoxin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Eye rolling
Hypotonia (low muscle tone)

10-19:

Skin discomfort (skin pain/irritation)

20-29:

n/a

30-39:

Drug exposure during pregnancy
Intra-uterine death
Premature labour

40-49:

Anxiety
Pain
Joint swelling
Headache (pain in head)
Injury
Blood glucose increased
Dyspnoea (difficult or laboured respiration)
Multiple injuries
Emotional distress
Muscle spasms (muscle contraction)

50-59:

Asthma
Bipolar disorder (mood disorder)
Blood cholesterol increased
Cardiac failure congestive
Cardiomegaly (increased size of heart than normal)
Cellulitis (infection under the skin)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

60+:

Hypertension (high blood pressure)
Pain
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
Diarrhoea
Injury
Nausea (feeling of having an urge to vomit)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Vision blurred
Anxiety

What are the existing conditions these people have? *

Cardiac Disorder: 5 people, 11.36%
Tachycardia Foetal (an abnormal increase in fetal heart rate and is variably defined as a heart rate above 160 -180 beats per minute): 4 people, 9.09%
Pain: 4 people, 9.09%
Maternal Therapy To Enhance Foetal Lung Maturity: 4 people, 9.09%
High Blood Pressure: 3 people, 6.82%
Heart Rate Irregular: 3 people, 6.82%
Cardiac Failure Congestive: 3 people, 6.82%
Asthma: 3 people, 6.82%

* Approximation only. Some reports may have incomplete information.

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