Imitrex and Flomax drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Imitrex (sumatriptan succinate) and Flomax (tamsulosin hydrochloride). Common drug interactions include malaise among females and blood glucose increased among males.

The phase IV clinical study analyzes what interactions people have when they take Imitrex and Flomax. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Imitrex?

Imitrex has active ingredients of sumatriptan succinate. It is often used in migraine. eHealthMe is studying from 17,149 Imitrex users. Check the latest studies of Imitrex.

What is Flomax?

Flomax has active ingredients of tamsulosin hydrochloride. It is often used in enlarged prostate. eHealthMe is studying from 52,865 Flomax users. Check the latest studies of Flomax.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 24, 2026

32 people who take Imitrex and Flomax together, and have interactions are studied.

What are the common drug interactions of Imitrex and Flomax, by gender? *:

female:

Malaise (a feeling of general discomfort or uneasiness)
Pregnancy
Abdominal pain
Aptyalism (deficiency or absence of saliva)
Blood pressure increased
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Colonic stenosis (abnormal narrowing of colon)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dehydration (dryness resulting from the removal of water)

male:

Blood glucose increased
Fatigue (feeling of tiredness)
Dyspnoea exertional (breathlessness or shortness of breath)
Dysuria (painful or difficult urination)
Haematocrit decreased
Haemoglobin decreased
Hypotension (abnormally low blood pressure)
Injury
Salivary gland cancer
Squamous cell carcinoma (a cancer of a kind of epithelial cell)

What are the common drug interactions of Imitrex and Flomax, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Pregnancy
Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
Urinary tract infection

30-39:

Back pain
Chest pain
Dysuria (painful or difficult urination)
Nausea (feeling of having an urge to vomit)
Abdominal pain
Alanine aminotransferase increased
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anger
Anxiety
Aspartate aminotransferase increased

40-49:

Blood pressure increased
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Fall
Haematochezia (passage of stools containing blood)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Headache (pain in head)
Lymphocyte count decreased
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Neutrophil count increased (excess than normal number of neutrophil a type of blood cell)

50-59:

Confusional state
Decreased appetite
Dizziness
Drug dependence
Drug ineffective
Dry eye (lack of adequate tears)
Dry mouth
Fatigue (feeling of tiredness)
Malaise (a feeling of general discomfort or uneasiness)
Mood swings (an extreme or rapid change in mood)

60+:

Blood glucose increased
Abdominal pain
Pain
Salivary gland cancer
Squamous cell carcinoma (a cancer of a kind of epithelial cell)
White blood cell count increased
Abdominal distension
Blood creatinine increased
Blood pressure increased
Constipation

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 10 people, 31.25%
Pain: 6 people, 18.75%
Quit Smoking: 2 people, 6.25%
Hypersensitivity: 2 people, 6.25%
Heart Disease: 2 people, 6.25%
Headache (pain in head): 2 people, 6.25%
Cluster Headache (one-sided head pain with tearing): 2 people, 6.25%
Blood Pressure Abnormal: 2 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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