Imitrex and Vesicare drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Imitrex (sumatriptan succinate) and Vesicare (solifenacin succinate). Common drug interactions include dyspepsia among females and headache among males.

The phase IV clinical study analyzes what interactions people have when they take Imitrex and Vesicare. It is created by eHealthMe based on reports of 48 people who take the same drugs from the FDA, and is updated regularly.

What is Imitrex?

Imitrex has active ingredients of sumatriptan succinate. It is often used in migraine. eHealthMe is studying from 17,149 Imitrex users. Check the latest studies of Imitrex.

What is Vesicare?

Vesicare has active ingredients of solifenacin succinate. It is often used in urge incontinence. eHealthMe is studying from 30,656 Vesicare users. Check the latest studies of Vesicare.



On Jul, 08, 2026

48 people who take Imitrex and Vesicare together, and have interactions are studied.

Imitrex and Vesicare drug interactions.

What are the common drug interactions of Imitrex and Vesicare, by gender? *:

female:

  1. Dyspepsia (indigestion)
  2. Dysphagia (a condition in which swallowing is difficult or painful)
  3. Ear discomfort
  4. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
  5. Erythema (redness of the skin)
  6. Eye swelling
  7. Flushing (the warm, red condition of human skin)
  8. Foot deformity (functional disability of foot)
  9. Gastric disorder (disease of stomach)
  10. Drug ineffective

male:

  1. Headache (pain in head)
  2. Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
  3. Malaise (a feeling of general discomfort or uneasiness)
  4. Myalgia (muscle pain)
  5. Nausea (feeling of having an urge to vomit)
  6. Neuropathy peripheral (surface nerve damage)
  7. Pain in extremity
  8. Poor quality sleep
  9. Somnolence (a state of near-sleep, a strong desire for sleep)
  10. Urinary tract infection

What are the common drug interactions of Imitrex and Vesicare, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Dyspnoea (difficult or laboured respiration)
  2. Pulmonary embolism (blockage of the main artery of the lung)
  3. Attention deficit/hyperactivity disorder
  4. Dizziness
  5. Haemorrhoids (a swollen vein or group of veins in the region of the anus)
  6. Incision site pain
  7. Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
  8. Paresis anal sphincter (a condition of muscular weakness of anal sphincter)
  9. Postoperative wound infection
  10. Rectal polyp (fleshy growth occurring on the lining of the colon)

40-49:

  1. Urinary tract infection
  2. Uterine disorder
  3. Vision blurred
  4. Vomiting
  5. Weight increased
  6. Abdominal distension
  7. Abdominal pain
  8. Abdominal pain upper
  9. Anxiety
  10. Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)

50-59:

  1. Muscular weakness (muscle weakness)
  2. Cystitis (inflammation of the wall of the bladder)
  3. Fall
  4. Nephrolithiasis (calculi in the kidneys)
  5. Drug ineffective
  6. Headache (pain in head)
  7. Oedema (fluid collection in tissue)
  8. Post procedural complication
  9. Asthenia (weakness)
  10. Asthma

60+:

  1. Drug ineffective
  2. Nausea (feeling of having an urge to vomit)
  3. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  4. Hypoaesthesia (reduced sense of touch or sensation)
  5. Loss of consciousness
  6. Pain
  7. Speech disorder
  8. Memory impairment
  9. Shoulder operation
  10. Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)

What are the existing conditions these people have? *

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 17 people, 35.42%
  2. Stress And Anxiety: 7 people, 14.58%
  3. Pain: 7 people, 14.58%
  4. Incontinence (lack of moderation or self-control): 4 people, 8.33%
  5. Headache (pain in head): 4 people, 8.33%
  6. Depression: 4 people, 8.33%
  7. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 6.25%
  8. High Blood Cholesterol: 3 people, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Imitrex and Vesicare?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Imitrex and Vesicare:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Imitrex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Vesicare:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Imitrex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vesicare and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on sumatriptan succinate and solifenacin succinate (the active ingredients of Imitrex and Vesicare, respectively), and Imitrex and Vesicare (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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