Imodium a-d and Alendronate sodium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Imodium a-d (loperamide hydrochloride) and Alendronate sodium (alendronate sodium). Common drug interactions include nausea among females and abdominal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Imodium a-d and Alendronate sodium. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.

What is Imodium a-d?

Imodium a-d has active ingredients of loperamide hydrochloride. It is often used in diarrhea. eHealthMe is studying from 8,944 Imodium a-d users. Check the latest studies of Imodium a-d.

What is Alendronate sodium?

Alendronate sodium has active ingredients of alendronate sodium. It is often used in osteoporosis. eHealthMe is studying from 43,608 Alendronate sodium users. Check the latest studies of Alendronate sodium.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

39 people who take Imodium a-d and Alendronate sodium together, and have interactions are studied.

Imodium a-d and Alendronate sodium drug interactions.

What are the common drug interactions of Imodium A-D and Alendronate Sodium, by gender? *:

female:

Nausea (feeling of having an urge to vomit)
Decreased appetite
Dehydration (dryness resulting from the removal of water)
Chest pain
Constipation
Rhinorrhoea (watery mucus discharge from the nose)
Bladder disorder
Blood glucose decreased
Dizziness
Fall

male:

Abdominal pain
Blood creatinine increased
Influenza
International normalised ratio increased
Lower gastrointestinal haemorrhage (bleeding in the large intestine, rectum, or anus is called lower gi bleeding)
Nephrolithiasis (calculi in the kidneys)
Red blood cell count decreased
Renal disorder (kidney disease)

What are the common drug interactions of Imodium A-D and Alendronate Sodium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Skin infection
Somnolence (a state of near-sleep, a strong desire for sleep)
Spinal stenosis (narrowing of spinal column)
Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
Tenderness (pain or discomfort when an affected area is touched)
Urinary tract infection
Wound infection
Abdominal distension
Abdominal pain lower
Aphasia (damage to the parts of the brain that control language)

60+:

Fatigue (feeling of tiredness)
Chest pain
Blood glucose decreased
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Constipation
Deafness
Dehydration (dryness resulting from the removal of water)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Dizziness
Ear pain

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 13 people, 33.33%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 15.38%
Multiple Myeloma (cancer of the plasma cells): 6 people, 15.38%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 12.82%
Idiopathic Pulmonary Fibrosis (chronic lung disease): 4 people, 10.26%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 7.69%
Breast Cancer Female: 3 people, 7.69%
Nausea (feeling of having an urge to vomit): 2 people, 5.13%
Migraine (headache): 2 people, 5.13%
Meniere's Disease (a disorder of the inner ear that can affect hearing and balance to a varying degree): 2 people, 5.13%

* Approximation only. Some reports may have incomplete information.

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