Imodium a-d and Vitamin b6 drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Imodium a-d (loperamide hydrochloride) and Vitamin b6 (pyridoxine). Common drug interactions include nervousness among females and nausea among males.

The phase IV clinical study analyzes what interactions people have when they take Imodium a-d and Vitamin b6. It is created by eHealthMe based on reports of 43 people who take the same drugs from the FDA, and is updated regularly.

What is Imodium a-d?

Imodium a-d has active ingredients of loperamide hydrochloride. It is often used in diarrhea. eHealthMe is studying from 8,944 Imodium a-d users. Check the latest studies of Imodium a-d.

What is Vitamin b6?

Vitamin b6 has active ingredients of pyridoxine. It is often used in stress and anxiety. eHealthMe is studying from 16,183 Vitamin b6 users. Check the latest studies of Vitamin b6.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

43 people who take Imodium a-d and Vitamin b6 together, and have interactions are studied.

Imodium a-d and Vitamin b6 drug interactions.

What are the common drug interactions of Imodium A-D and Vitamin B6, by gender? *:

female:

Nervousness
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Peripheral swelling
Radiculopathy (a set of conditions in which one or more nerves is affected and does not work properly)
Rhinorrhoea (watery mucus discharge from the nose)
Sjogren's syndrome (a disease that causes dryness in the mouth and eyes)
Skin ulcer
Stomatitis (inflammation of mucous membrane of mouth)
Tendon rupture (tear of tendon)
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)

male:

Nausea (feeling of having an urge to vomit)
Decreased appetite
Weight decreased
Weight increased
Asthenia (weakness)
Dizziness
Non-small cell lung cancer (type of epithelial lung cancer)
Abscess intestinal (collections of pus-intestinal)
Anaemia (lack of blood)
Ascites (accumulation of fluid in the abdominal cavity)

What are the common drug interactions of Imodium A-D and Vitamin B6, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Asthenia (weakness)
Blood bilirubin increased
Confusional state
Decreased appetite
Dehydration (dryness resulting from the removal of water)
Depression
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Liver disorder (liver diseases)
Nausea (feeling of having an urge to vomit)
Rash

50-59:

Dizziness
Neuropathy peripheral (surface nerve damage)
Bradyphrenia (neurological term referring to the slowness of thought common to many disorders of the brain)
Muscle spasms (muscle contraction)
Neoplasm progression (growth of tumour)
Platelet count decreased

60+:

Renal impairment (severely reduced kidney function)
Abdominal discomfort
Oedema peripheral (superficial swelling)
Pneumonia
Rash
Somnolence (a state of near-sleep, a strong desire for sleep)
Weight decreased
Weight increased
Cardiac failure
Dyspnoea (difficult or laboured respiration)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 14 people, 32.56%
Hypersensitivity: 7 people, 16.28%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 6 people, 13.95%
Indigestion: 5 people, 11.63%
Breast Cancer: 5 people, 11.63%
Pain: 5 people, 11.63%
High Blood Cholesterol: 5 people, 11.63%
Sleep Disorder: 5 people, 11.63%
Urinary Tract Infection: 4 people, 9.30%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 4 people, 9.30%

* Approximation only. Some reports may have incomplete information.

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