Imodium and Lopid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Imodium (loperamide hydrochloride) and Lopid (gemfibrozil). Common drug interactions include chest pain among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Imodium and Lopid. It is created by eHealthMe based on reports of 53 people who take the same drugs from the FDA, and is updated regularly.

What is Imodium?

Imodium has active ingredients of loperamide hydrochloride. It is often used in diarrhea. eHealthMe is studying from 45,092 Imodium users. Check the latest studies of Imodium.

What is Lopid?

Lopid has active ingredients of gemfibrozil. It is often used in high blood cholesterol. eHealthMe is studying from 9,700 Lopid users. Check the latest studies of Lopid.

On Jul, 10, 2026

53 people who take Imodium and Lopid together, and have interactions are studied.

What are the common drug interactions of Imodium and Lopid, by gender? *:

female:

Chest pain
Hallucination (an experience involving the perception of something not present)
Urinary tract infection
Dermatitis acneiform (dermatoses including acne vulgaris, rosacea, folliculitis, and perioral dermatitis)
Dyspnoea (difficult or laboured respiration)
Full blood count decreased
Impaired healing
Oral pain
Pneumonia
Weight increased

male:

Fatigue (feeling of tiredness)
Pneumonia
Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
Cardiac failure congestive
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Cough
Dehydration (dryness resulting from the removal of water)
Drug ineffective
Drug maladministration
Fall

What are the common drug interactions of Imodium and Lopid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Face oedema (swelling of face)
Urticaria (rash of round, red welts on the skin that itch intensely)
Vomiting

40-49:

Dehydration (dryness resulting from the removal of water)
Dermatitis acneiform (dermatoses including acne vulgaris, rosacea, folliculitis, and perioral dermatitis)
Neurological symptom (symptoms of nervous system disease)
Activated partial thromboplastin time prolonged
Body temperature increased
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Drug maladministration
Febrile neutropenia (fever with reduced white blood cells)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
International normalised ratio increased

50-59:

Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Anaemia (lack of blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Blood glucose increased
Blood magnesium decreased
Blood potassium decreased
Blood urea increased
Bone density decreased
Bone marrow failure

60+:

Dizziness
Decreased appetite
Pain
Chest pain
Staphylococcal infection (an infection with staphylococcus bacteria)
Weight increased
Dyspnoea (difficult or laboured respiration)
Hallucination (an experience involving the perception of something not present)
Urinary tract infection
Abdominal pain

What are the existing conditions these people have? *

Stress And Anxiety: 7 people, 13.21%
Sleep Disorder: 6 people, 11.32%
High Blood Pressure: 6 people, 11.32%
Pain: 5 people, 9.43%
Nausea (feeling of having an urge to vomit): 5 people, 9.43%
Hiv Infection: 5 people, 9.43%
Diabetes: 5 people, 9.43%
Seasonal Allergy (allergic condition due to certain season): 3 people, 5.66%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 5.66%
Renal Cell Carcinoma (a kidney cancer): 3 people, 5.66%

* Approximation only. Some reports may have incomplete information.

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