Imodium and Quinine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Imodium (loperamide hydrochloride) and Quinine (cinchona). Common drug interactions include nerve root compression among females and flatulence among males.

The phase IV clinical study analyzes what interactions people have when they take Imodium and Quinine. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Imodium?

Imodium has active ingredients of loperamide hydrochloride. It is often used in diarrhea. eHealthMe is studying from 45,092 Imodium users. Check the latest studies of Imodium.

What is Quinine?

Quinine has active ingredients of cinchona. It is often used in leg pain. eHealthMe is studying from 4,981 Quinine users. Check the latest studies of Quinine.

On Jul, 20, 2026

26 people who take Imodium and Quinine together, and have interactions are studied.

What are the common drug interactions of Imodium and Quinine, by gender? *:

female:

Nerve root compression
Oedema peripheral (superficial swelling)
Osteitis (a general term for inflammation of bone)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Osteolysis (dissolution of bone)
Osteonecrosis of jaw (death of bone of jaw)
Pain
Pelvic fracture
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)

male:

Flatulence (flatus expelled through the anus)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Neuropathic arthropathy (a progressive destruction of bone and joints)
Oedema (fluid collection in tissue)
Pain
Post inflammatory pigmentation change
Rash generalised (rash on most of body parts)
Rash macular (small, flat red spots)
Rash pruritic (redness with itching)
Skin exfoliation (removal of the oldest dead skin cells)

What are the common drug interactions of Imodium and Quinine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Dry skin
Emotional distress
General physical health deterioration (weak health status)
Joint contracture (a permanent shortening of a muscle or joint)
Joint range of motion decreased (disease of joint movement)
Neuropathic arthropathy (a progressive destruction of bone and joints)
Oedema (fluid collection in tissue)

50-59:

n/a

60+:

Pneumonia
Cardiac failure
Constipation
Death
Decreased appetite
Depression
Diabetes mellitus inadequate control
Dizziness
Drug hypersensitivity
Drug ineffective

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 6 people, 23.08%
Muscle Spasms (muscle contraction): 3 people, 11.54%
Rashes (redness): 2 people, 7.69%
Pain: 2 people, 7.69%
Nuclear Magnetic Resonance Imaging Abdominal: 2 people, 7.69%
Nausea (feeling of having an urge to vomit): 2 people, 7.69%
Itching: 2 people, 7.69%
High Blood Pressure: 2 people, 7.69%
Headache (pain in head): 2 people, 7.69%
Diabetes: 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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