Imodium and Viramune drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Imodium (loperamide hydrochloride) and Viramune (nevirapine). Common drug interactions include alanine aminotransferase increased among females and blood lactic acid increased among males.
The phase IV clinical study analyzes what interactions people have when they take Imodium and Viramune. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.
What is Imodium?
Imodium has active ingredients of loperamide hydrochloride. It is often used in diarrhea. eHealthMe is studying from 45,092 Imodium users. Check the latest studies of Imodium.
What is Viramune?
Viramune has active ingredients of nevirapine. It is often used in hiv infection. eHealthMe is studying from 11,381 Viramune users. Check the latest studies of Viramune.
44 people who take Imodium and Viramune together, and have interactions are studied.

What are the common drug interactions of Imodium and Viramune, by gender? *:
female:
- Alanine aminotransferase increased
- Aspartate aminotransferase increased
- Bilirubin conjugated increased
- Blood alkaline phosphatase nos increased
- Blood bilirubin increased
- Blood lactate dehydrogenase increased
- Gastroenteritis (inflammation of stomach and intestine)
- Hepatic failure (liver failure)
- Pain in limb
- Peripheral neuropathy (damage to nerves of the peripheral nervous system)
male:
- Blood lactic acid increased
- Hypertriglyceridaemia (excess of triglycerides in the blood)
- Agitation (state of anxiety or nervous excitement)
- Febrile convulsion (a convulsion associated with a significant rise in body temperature)
- Infection
- Leukopenia (less number of white blood cells in blood)
- Pain
- Speech disorder
- Neonatal disorder (disease of neonates)
- Pyrexia (fever)
What are the common drug interactions of Imodium and Viramune, by age (0-1 to 60+)? *:
0-1:
- Blood lactic acid increased
- Hypertriglyceridaemia (excess of triglycerides in the blood)
- Agitation (state of anxiety or nervous excitement)
- Blood creatine phosphokinase increased
- Cytomegalovirus infection
- Hepatosplenomegaly (enlargement of both the liver and the spleen)
- Hypocalcaemia (levels of calcium in blood serum are abnormally low)
- Neutropenia neonatal (an abnormally low number of neutrophils in below a month baby)
- Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
- Febrile convulsion (a convulsion associated with a significant rise in body temperature)
2-9:
- Anaemia (lack of blood)
- Blood creatine phosphokinase increased
- Blood lactic acid increased
- Complications of maternal exposure to therapeutic drugs
- Developmental delay
- Drug exposure during pregnancy
- Hypertriglyceridaemia (excess of triglycerides in the blood)
- Neonatal disorder (disease of neonates)
- Neutropenia neonatal (an abnormally low number of neutrophils in below a month baby)
10-19:
n/a
20-29:
n/a
30-39:
- Lipoatrophy (localized loss of fat tissue)
- Mouth ulceration (mouth ulcers)
- Muscle cramp (painful sensation caused by muscle contraction)
- Myalgia (muscle pain)
- Pain in extremity
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Pneumonia
- Pyrexia (fever)
- Tobacco abuse
- Vomiting
40-49:
- Abdominal pain
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Arthralgia (joint pain)
- Bacteriuria (presence of bacteria in urine)
- Blood creatinine increased
- Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
- Chronic kidney disease
- Coma (state of unconsciousness lasting more than six hours)
- Compression fracture (fracture due to pressure caused by injury)
50-59:
n/a
60+:
- Pancreatitis acute (sudden inflammation of pancreas)
- Asphyxia (a condition in which there is an extreme decrease in the concentration of oxygen in the body)
- Blood amylase increased
- Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
* Approximation only. Some reports may have incomplete information.
Do you take Imodium and Viramune?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Imodium and Viramune:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Imodium:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Viramune:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Imodium and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Viramune and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on loperamide hydrochloride and nevirapine (the active ingredients of Imodium and Viramune, respectively), and Imodium and Viramune (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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